A 40-year-old male presented with a history of low-grade fever, weight loss, night sweats and breathlessness of 3 months duration. On examination, the patient had freely mobile lump in left lumbar region. The lump was surgically excised. Histological examination and immunohistochemistry of the specimen were consistent with the diagnosis of plasma cell variant of the Castleman disease. The patie...

Introduction . Castleman disease (CD) is a rare lymphoproliferative disorder also known as angiofollicular lymph node hyperplasia or giant lymphoid hyperplasia. CD considered unicentric in the presence of single focus and if clinical picture represented by multiple lymphadenopathy systemic manifestations, it multicentric. Manifestation occurrence that mimics tumor meninges brain extremely rare,...

we present here a 32-year-old male with advanced lately diagnosed, right sided retroperitoneal mass, which had been already treated due to progressive muco-cutaneous lesions clinically consistent with psoriasis, during recent four years. the advanced retroperitoneal mass resected surgically and reported as hyaline-vascular castleman disease with a dense focus of coarse calcification, on histopa...

BACKGROUND AND AIMS Castleman's disease is a rare disorder situated at the boundary between reactive and neoplastic conditions. The pathogenesis is a subject of debate and the limited number of cases renders the study of the disease difficult. In our paper we present a series of six cases of Castleman disease with emphasis on the clinical presentation, pathology examination and the use of immun...

Bệnh Castleman (Castleman’ Desease – CD) là bệnh rối loạn tăng sinh của tổ chức hạch lympho, có thể gặp ở nhiều cơ quan khác nhau, tuy nhiên hiếm mạc treo ruột, tổn thương đa ổ hoặc đơn ổ, nguyên nhân không rõ ràng, rất khó chẩn đoán trước mổ và dễ nhầm với các khác. Điều trị phẫu thuật cắt bỏ tốt những trường hợp khu trú một ổ. Với còn lại phối điều tia xạ hóa liệu theo phác đồ CHOP.