objectives : platelet preparations are commonly used to enhance bone and soft tissue regeneration. considering the existing controversies on the efficacy of platelet products for tissue regeneration, more in vitro studies are required. the aim of the present study was to compare the in vitro effects of plasma rich in growth factors (prgf) and platelet-rich fibrin (prf) on proliferation and viab...

micrornas (mirnas) are a group of short non-coding rnas implicated in numerous fundamental cellular processes, and their disregulations have been linked to several pathologic conditions, mainly cancers. determining tissue distribution of mirnas is a prerequisite for understanding their exact functions during development, tissue homeostasis and abnormality. in situ hybridization is a powerful te...

objective(s):anodized treated titanium surfaces, have been proposed as potential surfaces with better cell attachment capacities. we have investigated the adhesion and proliferation properties of h9c2 cardiac myoblasts on anodized treated titanium surface.  materials and methods: surface topography and anodized tubules were examined by high-resolution scanning electron microscopy (sem). control...

objective: we studied both the presence of some carbohydrate compounds in a three-dimensional (3d) matrix harvested from human gingiva and the cell behavior in this matrix. materials and methods: in this experimental research, in order to prepare 3d scaffolds, human palatal gingival biopsies were harvested and physically decellularized by freeze-thawing and sodium dodecyl sulfate (sds). the sca...

human mesenchymal stem cells (hmscs), which also called mesenchymal stromal cells, are multipotent stem cell. human mscs typically are positive for the surface markers cd44, cd73, cd90, cd105, cd106, and also negative for hematopoietic markers cd34 and cd45.these cells can be isolated from postnatal bone marrow, adipose tissue, placenta, and scalp tissue, as well as from various fetal tissues. ...

stem/progenitor cell based therapeutic approach in our daily routine clinical practice, has been elusive dream in medical sciences and improvement of stem cell homing as one of major challenges in cell therapy programs, has been considered a promising milestone. it has been proved that stem/progenitor cells exhibit a homing response to injured tissues/organs, mediated by interactions of chemoki...

we are describing a new surgical approach in the management of advanced ocular surface cicatrization through a single procedure conjunctival-limbal-corneal allograft in which the external eye is resurfaced it involves a lamellar corneolimbal keratoplasty, 360° limbal stem cell transfer (on a “bipedicle” conjunctival-corneal carrier), and conjunctival tissue transplantation - all in a single con...

objective(s):osteoarthritis (oa) is globally one of the most common diseases from the middle age onwards. cartilage is an avascular tissue therefore it cannot be repaired in the body. conservative treatments have failed as a good remedy and cell therapy as a decisive cure is needed. one of the best and easily accessible cell sources for this purpose is adipose-derived stem cells which can be di...