Stroke is the world's largest neurological defect caused by the disruption of brain blood circulation. Apart from death, the severest damage caused by stroke, a plethora of other mental and physical disabilities can ensue the incidence of a stroke. As a result of the continued disruption of blood circulation triggered by a stroke, biochemical and physiological mechanisms affect nerve cells and ...

Background and objectives: Beside its nutritional role, caper (Capparis spinosa) has long been used as an analgesic, anti-inflammatory, anti-diabetic and anti-cancer remedy. In the present study, we tested whether this plant can make effective changes in Sirt3 and mitochondrial function in colorectal carcinoma cell line since mitochondrial dysfunction has long been imp...

background: functional defects in mitochondria are involved in the induction of cell death in cancer cells. the process of programmed cell death may occur through the mechanisms of apoptosis. several potential lead molecules such as camptothecin (cpt) and its analogues have been isolated from plants with anticancer effect. the aim of the present study was to understand the necrotic effect versu...