Secretory vesicles accumulate adjacent to the contact site between the two cells of a yeast mating pair before they fuse, but there is no direct evidence that secretion is required to complete fusion. In this study, temperature-sensitive secretion (sec(ts)) mutants were used to investigate the role of secretion in yeast cell fusion. Cell fusion arrested less than 5 minutes after inhibiting secr...

senescence has long been established as a stable and irreversible growth arrest, which plays an important role in tumor suppression and tissue repair. It can be induced by various stimuli, including telomere shortening, oncogene activation and oxidative stress. We recently demonstrated that cell-cell fusion is a previously unidentified trigger for inducing cellular senescence [1]. This work was...

a generalization of the known results in fusion frames and $g$-frames theory to continuous fusion frames which defined by m. h. faroughi and r. ahmadi, is presented in this study. continuous resolution of the identity (cri) is introduced, a new family of cri is constructed, and a number of reconstruction formulas are obtained. also, new results are given on the duality of continuous fusion fram...

abstract  background: spondylolysis and spondylolisthesis can be associated with significant  low back pain, especially in physically active adolescents. non-operative management  is usually successful in improving symptoms, but surgical intervention is  occasionally required. the aim of this study was to determine the effect of in situ posterolateral  fusion in the treatment of refractory case...

Membrane fusion plays a key role in many biological processes including vesicle trafficking, synaptic transmission, fertilization or cell entry of enveloped viruses. As a common feature the fusion process is mediated by distinct membrane proteins. We describe here 'Fusoselect', a universal procedure allowing the identification and engineering of molecular determinants for cell-cell fusion-activ...

splenogonadal fusion is a rare entity with approximately 150 reported cases until the year 2005. the entity is a rare congenital anomaly in which there is fusion of splenic and gonadal anlagen or mesonephric derivatives. splenogonadal fusion has two continuous and discontinuous types. about ten cases have been reported to be associated with bilateral cryptorchidism in literature. very few cases...

Cell fusions produce multinucleate syncytia that are crucial to the structure of essential tissues in many organisms [1-5]. In humans the entire musculature, much of the placenta, and key cells in bones and blood are derived from cell fusion. Yet the developmental fusion of cell membranes has never been directly observed and is poorly understood. Similarity between viral fusion proteins and rec...

Cell-cell fusion proteins are essential in development. Here we show that the C. elegans cell-cell fusion protein EFF-1 is structurally homologous to viral class II fusion proteins. The 2.6 Å crystal structure of the EFF-1 trimer displays the same 3D fold and quaternary conformation of postfusion class II viral fusion proteins, although it lacks a nonpolar "fusion loop," indicating that it does...

In this paper we investigate a new notion of bases in Hilbert spaces and similar to fusion frame theory we introduce fusion bases theory in Hilbert spaces. We also introduce a new denition of fusion dual sequence associated with a fusion basis and show that the operators of a fusion dual sequence are continuous projections. Next we dene the fusion biorthogonal sequence, Bessel fusion basis, Hil...