BACKGROUND The proliferation of clonal cytotoxic T-cells or natural killer cells has been observed after dasatinib treatment in small studies of patients with chronic myeloid leukemia (CML). METHODS The incidence of lymphocytosis and its association with response, survival, and side effects were assessed in patients from 3 large clinical trials. Overall, 1402 dasatinib-treated patients with n...

Etude de deux cas d'Hyperlymphocytose in­fectieuse benigne consernant de deux enfants subfebriles, Sans adenopathies ni Hepato-SplenG---­ megalie confirmee par les examens bi.ologiques et en particulier Etude cytologique de la moele osseuse;  Amelioration clinique et Hematologique de fac;on spontanee sans Traitement. 

Bronchoalveolar lavage (BAL) has been crucial in elucidating the immune effector cells involved in the inflammatory processes in idiopathic interstitial pneumonias [1]. Despite its value as a research tool, the diagnostic usefulness of BAL in idiopathic interstitial pneumonias is limited. An increase in neutrophils and/or eosinophils and/or lymphocytes may be seen. The idiopathic interstitial p...

introduction: the most common symptom of brucellosis is osteoarticular manifestation. urogenital manifestation, hepatitis, cns and respiratory system involvement and endocarditis are also reported. mild leukopenia with lymphocytosis, anemia, thrombocytopenia and seldom pancytopenia is seen. case presentation: a 22-year-old man with fever and chills, abdominal pain and diarrhea came to the hospi...

Hypersensitivity to mosquito bites (HMB) is characterized by intense skin reactions at bite sites. The pathogenesis of HMB might be related to clonal lymphoproliferation of Epstein-Barr virus DNA-positive natural killer (NK) cells. We report the first case of HMB possibly associated with NK cell-derived large granular lymphocyte (NK-LGL) lymphocytosis in Korea.

1. In mice rendered lymphocytopenic by X-irradiation or hydrocortisone acetate, pertussis vaccine evoked both lymphocytosis and polymorphonuclear leukocytosis. 2. When mice with lymphocytosis induced by pertussis vaccine were X-irradiated, prompt and extensive destruction of circulating as well as tissue small lymphocytes occurred. The devitalized circulating cells were cleared from the blood p...

various changes have been noted in the lymphatic system during infection. The paper by Sprunt and Evans2 in 1920 and the subsequent discovery twelve years later of heterophile antibodies in the serum of patients with infectious mono-nucleosis3 stimulated renewed interest in the problem. Data from most laboratories show that the leucocytes rarely pass a level of 20,000 and that there is an "incr...

The immune response to Mycobacterium tuberculosis is mediated by T lymphocytes. We studied the changes in lymphocyte populations occurring in peripheral blood, pleural fluid, and ascites during tuberculosis infection. For this purpose, we compared recent-onset patients (newly converted to positive Mantoux reactions) with previously diagnosed patients (individuals with organic lesions). Recent i...