cystic fibrosis (cf), the most common life-shortening, hereditary disease in whites, manifests itself principally in childhood. patients presenting with cf as adults appear to be different when compared to patients diagnosed with cf during childhood. often these patients have been previously diagnosed with asthma, chronic bronchitis or emphysema. we present a case of a woman diagnosed with cf a...

Sleep apnea syndrome is characterized by recurrent episodes of oxygen desaturation and reoxygenation (intermittent hypoxia [IH]) and is a risk factor for insulin resistance/type 2 diabetes. However, the mechanisms linking IH stress and insulin resistance remain elusive. We exposed human hepatocytes (JHH5, JHH7, and HepG2) to experimental IH or normoxia for 24 h, measured mRNA levels by real-tim...

Epithelial-mesenchymal transition (EMT) has been recognized as a key element of cell migration, invasion, and drug resistance in several types of cancer. In this study, our aim was to clarify microRNAs (miRNAs)-related mechanisms underlying EMT followed by acquired resistance to chemotherapy in glioblastoma (GBM). We used multiple methods to achieve our goal including microarray analysis, qRT-P...

Many people want to change the rules when they look at the right heart. My perception is that the very same rules should be applied perhaps more stringently when considering any method of assessment ofright heart function. The variable shape ofthe human right ventricle makes it more difficult by every method The concept advanced by Albert is a myth about gated blood pool ventriculography which ...

Based on the controversial beliefs among L2 teachers about effective corrective feedback (CF) strategies, recast and prompts as 2 kinds of CF have drawn the attention of L2 researchers(e.g., Braidi, 2002; Iwashita, 2003; Loewen & Philp, 2006; Panova & Lyster, 2002; Sheen, 2004). Despite these numbers of studies, debate continues to exist about their usefulness as a CF technique. Whereas recasts...

A candidate antitumor agent, 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F-203), was empirically discovered through the National Cancer Institute's Anticancer Drug Screen from a unique growth inhibitory-response profile, indicating a novel mechanism of action. 5F-203 activates the CYP1 family of cytochrome P450, involving aryl hydrocarbon receptor translocation into the nucleus. To chara...

a bstract background: nurses are at risk for symptoms of compassion fatigue (cf) and burnout (bo). social support plays an important role in predicting cf and bo. this study was performed to determine the prevalence of the symptoms of cf and bo and the role of perceived social support in predicting these symptoms in iranian nurses. materials and methods: using a correlational descriptive survey...