BACKGROUND A practitioner questioned whether moisture that collected in the ventilator circuit and spacer affected the delivery of aerosol from a pressurized metered-dose inhaler (pMDI). An in vitro model was used to quantify the impact of accumulated humidity in a pMDI spacer and ventilator over time. METHODS A ventilator with an adult heated-wire ventilator circuit and humidifier was set to...

In magnetic multilayers, the magnetizations of two ferromagnetic layers separated by a non-magnetic spacer layer are coupled by the electrons in the spacer layer. This coupling oscillates in sign as a function of the thickness of the spacer layer. Extensive research done on these systems has led to a simple model for this coupling and remarkable agreement between predictions of the model and me...

using of nanofluids and ducts with corrugated walls are both supposed to enhance heat transfer, by increasing the heat transfer fluid conductivity and the heat transfer area respectively. use of a diverging duct with a jet at inlet section may further increase heat transfer by creating recirculation zones inside the duct. in this work two-dimensional incompressible laminar flow of a nanofluid e...

Nuclear factor I (NFI) is a site-specific DNA binding protein required for the replication of adenovirus type 2 DNA in vitro and in vivo. To study sequence requirements for the interaction of NFI with DNA, we have measured the binding of the protein to a variety of synthetic sites. Binding sites for NFI (FIB sites) were previously shown to contain a consensus sequence composed of 2 motifs, TGG ...

Rare individuals of Xenopus laevis exhibit frequent initiation of transcription in the spacers of oocyte ribosomal DNA (rDNA). Using electron microscopy we have characterized spacer transcription in such an individual and have confirmed that the sites of transcription initiation correspond to the imperfectly duplicated promoters ("Bam islands") present in the X. laevis rDNA spacer. We have clon...

The composition of bacterial populations in copper bioleaching systems was investigated by analysis of DNA obtained either directly from ores or leaching solutions or after laboratory cultures. This analysis consisted of the characterization of the spacer regions between the 16 and 23S genes in the bacterial rRNA genetic loci after PCR amplification. The sizes of the spacer regions, amplified f...

OBJECTIVES To investigate bacterial contamination in spacer devices used by asthmatic children and the device maintenance procedures practiced by parents. METHODS Spacer devices used by 62 asthmatic children were examined. Swabs taken from the inner surface of the reservoirs and face masks were cultured. Parents were interviewed regarding their spacer cleaning and disinfection routines. RES...

BACKGROUND AND PURPOSE Antibiotic-loaded cement spacers are typically manufactured by surgeons in the operating room. However, if the infecting organism is known preoperatively, the cement spacer can be fabricated (Spacer-G(®) or the InterSpace(®) Hip) in advance. It is unclear if preformed hip spacers are superior to surgeon-made hip spacers in the treatment of periprosthetic joint infection f...