Apparent central apnoea (absent breathing movements) detected by monitoring movement of the thoracic wall was compared with simultaneous detection by abdominal wall movement. Eighteen infants provided one or more 24 hour recording of heart rate (electrocardiography), thoracic respiration (transthoracic impedance), and abdominal wall movement (pressure sensitive capsule distortion). Detection of...

The yeast cell wall is constantly remodeled to enable cell growth and division. In this study, we describe a novel type of cell wall modification. We report that the drug amiodarone induces rapid channel formation within the cell wall of the yeast Hansenula polymorpha. Light microscopy shows that shortly after adding amiodarone, spherical structures, which can be stained with DNA binding dyes, ...

A new adaptive controller based on a neural network was constructed and applied to turbulent channel flow for drag reduction. A simple control network, which employs blowing and suction at the wall based only on the wall-shear stresses in the spanwise direction, was shown to reduce the skin friction by as much as 20% in direct numerical simulations of a low-Reynolds number turbulent channel flo...

Dielectrophoresis has shown a wide range of applications in microfluidic devices. Force approximations utilizing the point-dipole method in dielectrophoresis have provided convenient predictions for particle motion by neglecting interactions between the particle and its surrounding electric and flow fields. The validity of this approach, however, is unclear when the particle size is comparable ...

Objective: To investigate the relation between the wall motion abnormalities and sodium channel abnormalities in cases of the Brugada syndrome. Design: Consecutive prospective case–control study in a single hospital. Setting: Tertiary referral centre. Patients: 13 consecutive patients with Brugada syndrome and 13 age and sex matched control subjects. Interventions: Each subject underwent electr...

State estimation of turbulent near-wall flows based on wall measurements is one of the key pacing items in model-based flow control, with low-Re channel flow providing the canonical testbed. Model-based control formulations in such settings are often separated into two subproblems: estimation of the near-wall flow state via skin friction and pressure measurements at the wall, and (based on this...

Turbulent forced convective mass (heat) transfer downstream of blockages with round and elongated holes in a rectangular channel was studied. The blockages and the channel had the same 12:1 (width-to-height ratio) cross section, and a distance equal to twice the channel height separated consecutive blockages. The diameter of the holes was either 0.5 or 0.75 of the height of the channel. Naphtha...

The wall-modeled large-eddy simulation (WMLES) computational framework generally includes a wall-model solver outside the (LES) infrastructure, with two solvers communicating only at matching location and wall. Having LES jeopardizes performance of WMLES: first, adds significant overhead; second, solution in wall-adjacent cell is ambiguous; third, it very difficult to utilize emerging high-orde...

To investigate flow of gas mixtures through micro channel in detail, the tangential momentum accommodation coefficients of each species for gaseous mixtures were determined by analyzing the Couette flow problem of a slightly rarefied gas between two walls. The molecular dynamics (MD) method for the interaction of gas molecule with the wall surface is combined with the DSMC method for the motion...

The effect of fluctuations on the conductivity of ion channels is investigated. It is shown that modulation of the potential barrier at the selectivity site due to electrostatic amplification of charge fluctuations at the channel mouth exerts a leading-order effect on the channel conductivity. A Brownian dynamical model of ion motion in a channel is derived that takes into account both fluctuat...