نتایج جستجو برای: chemoimmunotherapy
تعداد نتایج: 698 فیلتر نتایج به سال:
The antigenicity and immunogenicity of three colorectal carcinomas induced in BALB/c mice by 1,2-dimethylhydra zine orN-methyl-N-nitrosourethan were studied. All tumors were readily transplantable. Two of these tumors metasta sized when transplants reached sufficient size. All tumors were found to be immunogenic in the strain of origin, and all tumors were shown to contain unique tumor-specific...
Younger patients (defined as patients younger than 50-55 years of age) represent a small group of newly diagnosed patients with chronic lymphocytic leukemia, accounting only for 10% to 20% of newly diagnosed cases. However, once these patients become symptomatic and require treatment, their life expectancy is significantly reduced. Therapeutic approaches for younger patients should be directed ...
We evaluated PROs in the real-world setting for patients informCLL registry receiving treatment CLL/SLL. Eligible were enrolled from 178 sites (10/2015-06/2019). assessed using FACT-G questionnaire (score range, 0-108; higher scores indicate better QoL; minimally important difference change total score: 5 points). Scores at baseline and 6 12 months on study by line of therapy (LOT) treatment. D...
Chemoimmunotherapy has resulted in high complete remission rates and long remission duration in patients with chronic lymphocytic leukemia (CLL) but relapses occur and curative strategies still need to be developed. A wealth of new agents with a wide variety of mechanisms of action against CLL are currently in clinical trials. Twelve of these agents, which are in various stages of development v...
Dendritic cell-derived exosomes (DEX) are nanomeric vesicles harboring MHC/peptide complexes capable of promoting primary T cell responses and tumor rejection in the presence of adjuvants. In this study, we show that, in the absence of adjuvants, DEX mediate potent Ag-dependent antitumor effects against preestablished tumors in mice pretreated with immunopotentiating dosing of cyclophosphamide....
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