The behavior of chlordiazepoxide has been studied using dc-polarography at dropping mercury electrode (DME) and cyclic voltammetry at glassy carbon electrode (GCE). In Britton-Robinson buffers, the drug developed three reduction irreversible waves in acidic solutions, and only two waves in alkaline media. The adsorptive stripping voltammetric behavior of chlorodiazepoxide was studied at GCE, an...

hydrochloride (10 mg three times a day for as long as 20 days) did not affect values for 17-hydroxycorticosteroids. In vitro data do show that there is a small increase in the apparent value for urinary 17-hydroxycorticosteroids when chlordiazepoxide or its lactam or N-despiethyl metabolite is added to urine. However, this increase does not appear to be large enough to be of significance. The f...