The formation of new capillaries (angiogenesis) may be of clinical importance in facilitating reperfusion and regeneration of hibernating cardiac tissue after myocardial infarction and in microvascular ischemia. Evidence is accumulating that as part of the response to hypoxia, bone marrow-derived circulating endothelial progenitor cells (CEPs) are mobilized and subsequently differentiate into p...

Philip M. Chang, MD, FHRS, CEPS, Akash R. Patel, MD, FHRS, CEPS, Peter Aziz, MD, FHRS, CEPS, Maully J. Shah, MBBS, FACC, FHRS From the Keck School of Medicine of University of Southern California (USC), Keck Medical Center of USC, Los Angeles, California, University of California San Francisco (UCSF) School of Medicine, UCSF Benioff Children’s Hospital, San Francisco, California, Cleveland Clin...

Reaction with thiol converts the antitumor natural product leinamycin to an episulfonium ion that alkylates the N(7)-position of guanine residues in double-stranded DNA. The sequence specificity for DNA alkylation by this structurally novel compound has not previously been examined. It is reported here that leinamycin shows significant (>10-fold) preferences for alkylation at the 5'-G in 5'-GG ...

A vicinal ethylene bridged S/B frustrated Lewis pair (FLP) in situ generated by a hydroboration reaction of phenyl vinyl sulfide, reacts with p-tert-butylphenylacetylene by ethene/alkyne exchange and subsequent 1,2-addition of a second alkyne equivalent to give a zwitterionic sulfonium/borate product.

The appearance of 'filler syllables' (called here PAEs, for Prefixed Additional Elements) in the late single-word period is analysed in relation to the emergence of grammatical morphemes, by confronting data from the longitudinal study of one child acquiring French, video-recorded between 1;3.2 and 2;2.6, with four hypotheses making different claims about the kind of language knowledge underlyi...

Evolutionary algorithms have been widely used to solve large and complex optimisation problems. Cultural algorithms (CAs) are evolutionary algorithms that have been used to solve both single and, to a less extent, multiobjective optimisation problems. In order to solve these optimisation problems, CAs make use of different strategies such as normative knowledge, historical knowledge, circumstan...

Chiral exceptional points (CEPs) have been shown to emerge in traveling wave resonators via asymmetric back scattering from two or more nano-scatterers. Here, we provide a new perspective on the formation of CEPs based coupled oscillator model. Our approach provides an intuitive understanding for modal coalescence that signals emergence CEPs, and emphasizes role played by dissipation throughout...

In this work, ZnCaO2 (zinc oxide-calcium oxide) nanocomposite were synthesized at different temperatures (500-700°C) by sol-gel method based on polymeric network of polyvinyl alcohol (PVA). The synthesized samples were characterized by SEM/EDAX, FT-IR and XRD techniques. It was found that synthesized nanocomposites have 1.62, 2.05 and 13.91%wt of CaO, respectively. The obtained results show tha...

transmitted in any form or by any means without the prior permission in writing of the publisher nor be issued to the public or circulated in any form other than that in which it is published. In the UK there has historically been a clear demarcation between the academic and vocational routes through education post-16. Generally vocational study is taken either on a part time basis or full time...

This paper analyses the stock market linkages of the selected Central and Eastern European (CEE) markets (Czech Republic – PX, Hungary – BUX and Poland – WIG20) with the Western European stock market represented by the German DAX and studies also the comovement between the individual CEE countries’ stock markets. The dynamic conditional correlation (DCC) models were used to model the co-movemen...