نتایج جستجو برای: chorioallantoic membrane
تعداد نتایج: 389299 فیلتر نتایج به سال:
In vivo detection of cancer at an early-stage, i.e. smaller than 2 mm, is a challenge in biomedicine. In this work target labeling of an early-stage tumor spheroid (∼500 μm) is realized for the first time in a chick embryo chorioallantoic membrane (CAM) model with monoclonal antibody functionalized upconversion nanoparticles (UCNPs-mAb).
A series of Combretastatin A-4 analogues were synthesized in order to obtain new compounds with potential antiangiogenic activity. The structures of all synthesized compounds were confirmed by means of spectroscopical analytical techniques. All compounds were evaluated for their antiangiogenic activity by chorioallantoic membrane (CAM) assay method. The compounds showed significant antiangiogen...
Due to the limitations of bone autografts, we aimed develop new composite biomaterials with pro-angiogenic and osteogenic properties be used as scaffolds in tissue engineering applications. We a porous, cross-linked slowly biodegradable fibrin/alginate scaffold originally developed our laboratory for wound healing, throughout which deposits calcium phosphate (CaP) were evenly incorporated using...
The chicken Chorioallantoic membrane was used to select variant tumor cell subpopulations from the murine melanoma B16-BL6 and the rat glioma C6 cell lines. Tumor cells were deposited on the chicken Chorioallantoic membrane of eggs 10 days postfertilization. Upon hatching, chickens were autopsied, and organs were removed, minced, and implanted s.c. in C57BL/ 6J mice (for melanoma) or nude mice ...
This paper describes the growth of HEp-3, a human epidermoid carcinoma, in the chick embryo. When inoculated onto the chorioallantoic membrane, the tumor grows locally with a doubling time of 21 to 24 hr and disseminates widely in the embryo proper, metastasis to the lung and heart being espe cially prominent. The tumor secretes large amounts of plasminogen activator (PA) both in vivo and in vi...
The accompanying report (Watanabe, M., A. L. Frelinger III, and U. Rutishauser, 1986, J. Cell Biol., 103:1721-1727) describes a set of monoclonal antibodies (mAbs) directed against N-CAM epitopes representing the known major structural and functional domains of the molecule. In this study, we have generated and separated a variety of peptide fragments from N-CAM, and then used their size and re...
OBJECTIVE The distribution of cardiac output to different organs is well described in the mammalian fetus. Chick embryos are not often used in perinatal cardiovascular research and therefore it is not known whether they can serve as an animal model for this purpose. In this study we documented cardiac output distribution in chick embryos at increasing incubation time. METHODS Fertilized eggs ...
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