Using a recombinant product from the structurally abnormal Y chromosome, Y*, female mice with a single X of either maternal or paternal origin were generated. The two types of females were produced on the same genetic background and differ only in the origin of the X chromosome. Hence it has been possible to assess the effect of parental origin of the X on survival of females with a single X ch...

Spatial organization of chromosome territories is important for maintenance of genomic stability and regulation of gene expression. Recent studies have shown tissue-specific features of chromosome attachments to the nuclear envelope in various organisms including malaria mosquitoes. However, other spatial characteristics of nucleus organization, like volume and shape of chromosome territories, ...

Genetic determinants of sex in placental mammals developed by the evolution of primordial autosomes into the male and female sex chromosomes. The Y chromosome determines maleness by the action of the gene SRY, which encodes a protein that initiates a sequence of events prompting the embryonic gonads to develop into testes. The X chromosome in the absence of a Y chromosome results in a female by...

klinefelter syndrome includes a group of chromosomal disorders with at least one  additional  x  chromosome  in  male  karyotype  (46,xy).  up  to  now, different dental manifestations such as taurodontism, congenital absence of permanent teeth, shovel incisors, occlusal anomalies and increased permanent tooth size have been reported. a case of klinefelter syndrome with very rare dental feature...

The human X chromosome is the favorite chromosome of many geneticists because of its peculiar inheritance pattern and unique biology. The peculiar inheritance pattern stems from its hemizygosity in males and gives rise to a disproportionately high number of Mendelian diseases associated with a human chromosome. As high as 70% of the genes with a known function on the X are associated with disea...

Objective: Infertility is defined as absence of a healthy baby or pregnancy despite one-year regular unprotected sexual intercourse. While primary infertility called the at all, secondary inability couples who have had least one child to become pregnant. Chromosome anomalies are an important cause both male and female infertility. In this study, we aimed discuss results chromosome analysis with...