Following interferon-based therapy for chronic hepatitis C, the negativity of hepatitis C virus RNA is essential to achieve viral clearance at the end of treatment. We report a case of clearance of chronic hepatitis C virus infection following early discontinuation (at 6 weeks) of peginterferon plus ribavirin therapy, without negativity for hepatitis C virus RNA during the treatment period. The...

Liver disease, particularly viral hepatitis, is increasingly common. The most frequent causes of long-term, or chronic, viral hepatitis are persistent infections with the hepatitis B or hepatitis C virus. Worldwide, 400 million people are chronic carriers of the hepatitis B virus [1]. Each year, between 500,000 to 1.2 million people die from progression of this viral infection, making it the 10...

prevalence of chronic hepatitis c virus infection in adult multitransfused thalassemic patients in iran

INTRODUCTION Chronic hepatitis is a liver disease in the form of continuous inflammation and necrosis for at least 6 months. There are many causes of chronic hepatitis, including genetic disorders, drugs, toxins, autoimmune, idiopathic; but the most common cause is viral. The virus that causes chronic viral hepatitis is the hepatitis B virus (HBV), hepatitis C virus (HCV), as well as hepatitis ...

introduction: hepatitis c virus (hcv) is the major cause of acute and chronic hepatitis, cirrhosis, and hepatocellular carcinoma worldwide. because of increasing number of infected patients throughout the world, various studies are concentrated on development of high quality diagnostic tests and genotyping in various regions of the world. methods: in this study, we used rt-pcr to isolate and a...

objectives the aim was to study the prevalence of thrombocytopenia in hcv patients without cirrhosis and splenomegaly. patients and methods a cross-sectional study was carried out in the gastrointestinal out patient department (g.i. opd) of the sindh institute of urology and transplantation (siut) from september-november 2013. 30 patients aged between 18 - 60 years with a positive anti-hcv resu...

BACKGROUND/AIMS Polymorphism at the IL28B gene may modify the course of hepatitis C virus (HCV) chronic infection. Our aim was to study the influence of IL28B rs12979860 gene polymorphism on the biochemistry and pathology of HCV-induced disease in the clinical course from mild chronic hepatitis C to hepatocellular carcinoma. METHODS We have determined the rs12979860 single nucleotide polymorp...

background: hepatitis e virus is an enterically transmitted virus that is endemic in south asia and this virus is one of the most important cause of acute hepatitis in this region. although hepatitis e virus (hev) is not a leading cause for chronic hepatitis, the role of hev in exacerbation of chronic liver disease is certain. materials and methods: 100 cirrhotic cases (50 hepatitis b and 50 he...