نتایج جستجو برای: chronic periodontitis
تعداد نتایج: 505244 فیلتر نتایج به سال:
Recent studies investigating protease-activated receptor type 2 (PAR-2) suggest an association between the receptor and periodontal inflammation. It is known that gingipain, a bacterial protease secreted by the important periodontopathogen Porphyromonas gingivalis can activate PAR-2. Previous studies by our group found that PAR-2 is overexpressed in the gingival crevicular fluid (GCF) of patien...
Gene polymorphism of cytokines influencing their function has been known as a contributing factor in the pathogenesis of inflammatory diseases of the tooth and implant supporting tissues. The aim of this study was to investigate the association of IL-17R gene polymorphism (rs879576) with chronic periodontitis and periimplantitis in an Iranian population. 73 patients with chronic periodontitis, ...
Anemia of chronic disease (ACD) is defined as anemia occurring in chronic infections, inflammatory conditions or neoplastic disorders that are not due to marrow deficiencies or other diseases, and occurring despite presence of adequate iron stores and vitamins. The main underlying reason for ACD is previous chronic inflammation or infection. The present study was conducted to evaluate and compa...
Background: Periodontal diseases are among the most frequent diseases affecting children and adolescents. These include gingivitis, localized or generalized aggressive periodontitis (a.k.a., early onset periodontitis which includes generalized or localized prepubertal periodontitis and juvenile periodontitis) and periodontal diseases associated with systemic disorders. The best approach to mana...
BACKGROUND Inflammatory processes are considered to participate in the development of cardiovascular disease (CVD). Statins have been used successfully in the prevention and treatment of coronary heart disease. Chronic periodontitis has been suggested to contribute to CVD. The aim of this study was to examine the association of statin use and clinical markers of chronic periodontitis. METHODS...
We read the article published by Androsz-Kowalska et al. [1] with great interest. They investigated the mean platelet volume (MPV) in patients with chronic periodontitis with coronary artery disease (CAD), chronic periodontitis without CAD, and control subjects. They found that MPV was significantly higher in patients with chronic periodontitis with CAD than in controls. However, there was no s...
BACKGROUND The diagnosis of the progression of periodontitis presently depends on the use of clinical symptoms (such as attachment loss) and radiographic imaging. The aim of the multicenter study described here was to evaluate the diagnostic use of the bacterial content of subgingival plaque recovered from the deepest pockets in assessing disease progression in chronic periodontitis patients. ...
Background and Aim: Increased levels of receptor activator of nuclear factor kappa-B ligand (RANKL) and RANKL/OPG (osteoprotegerin) ratio in untreated periodontitis have been presented. However, current knowledge of periodontal treatment on osteoimmunological results is scarce. This study, aims to determine the RANKL, OPG, interleukin-1 beta (β), interleukin-10 levels in gingival crevicular flu...
Aim: Local bacteria stimulate polymorphonuclear neutrophils to release reactive oxygen species in periodontitis. Increased levels of oxidative stress play a significant role in the pathogenesis of periodontitis. Therefore, this study aimed to evaluate total salivary and serum antioxidant capacity and malondialdehyde in patients with chronic periodontitis. Materials and methods: Fifty-five healt...
BACKGROUND The involvement of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which converts inactive glucocorticoids into active glucocorticoids intracellularly, in metabolic diseases and chronic inflammatory diseases has been elucidated. We recently reported that an increase in 11β-HSD1 expression was associated with chronic periodontitis in humans irrespective of obesity. To further clar...
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