The aim of this study was to evaluate the effects of Atorvastatin on negative symptoms in patients with chronic schizophrenia. The study was a prospective, double-blind, 6-week trial. Forty patients participated in the study; 19 patients were assigned to the Atorvastatin group as well as 21 patients to the placebo group. For assessing negative signs, we used Scale for the Assessment of Negative...

The treatment of two chlorpromazine-medicated chronic schizophrenics with cimetidine resulted in excessive sedation, which necessitated a reduction in chlorpromazine dosage. Eventual discontinuation of cimetidine therapy led to a return of schizophrenic symptoms, which responded to an increase in chlorpromazine dosage to previous levels.

Two cohorts of male veteran patients with schizophrenia were compared on several clinical and demographic measures. The first cohort, hospitalized in one of two Veterans Affairs hospitals between 1965 and 1975, consisted largely of Korean-era veterans. The second cohort, hospitalized between 1991 and 1994, were largely Vietnam-era veterans. Although treatment and management of patients with sch...

Background Significant cognitive impairment has been considered a core characteristic of schizophrenia. Though many studies have reviewed the phenomenon, only a few Indian studies have investigated this aspect. Aims To compare the functioning of six cognitive domains of patients with chronic schizophrenia with an age, sex and education matched control group and to assess the association of soci...

OBJECTIVE Few studies have examined medical comorbidity among middle-aged and older homeless people with schizophrenia. This study compared the number of physical health problems and receipt of physical health care services among older homeless people with schizophrenia and those with major depression. METHODS The study was conducted at St. Vincent de Paul Village, a homeless shelter in San D...

Background: Schizophrenia is a chronic, debilitating psychiatric disorder which one of the leading causes disability worldwide and has large impact on individuals, families society. There paucity literature usefulness Homoeopathy in Schizophrenia.
 Cases summary: Two cases are assessed symptomatically using Positive Negative Syndrome Scale (PANSS) treated Psychiatry Department (blinded for...

Individuals with schizophrenia often demonstrate theory of mind (ToM) impairment relative to healthy adults. However, the exact nature of this impairment (first- vs. second-order ToM and cognitive vs. affective ToM) and the extent to which ToM abilities deteriorate with illness chronicity is unclear. Furthermore, little is known about the relationships between clinical symptoms and ToM error ty...

BACKGROUND Mismatch negativity (MMN) is an event-related brain potential that is sensitive to stimulus deviation from a repetitive pattern. The MMN is thought primarily to reflect the activity of sensory memory, with, at most, moderate influences of higher-level cognitive processes, such as attention. The MMN is reported to be reduced in patients with chronic schizophrenia. However, it is unkno...

Two of the most frequently investigated regions in diffusion tensor imaging studies in chronic schizophrenia are the uncinate fasciculus (UF) and cingulum bundle (CB). The purpose of the present study was to determine whether UF and CB white matter integrity were altered at the early stage of illness and specific to schizophrenia. Fifteen schizophrenia subjects and 15 affective psychosis within...