Chrysin is a 5,7-dihydroxyflavone and was recently shown to potently inhibit enterovirus 71 (EV71) by suppressing viral 3C protease (3C(pro)) activity. In the current study, we investigated whether chrysin also shows antiviral activity against coxsackievirus B3 (CVB3), which belongs to the same genus (Enterovirus) as EV71, and assessed its ability to prevent the resulting acute pancreatitis and...

Eugenia jambolana is a traditional medicinal plant of low reaches of Kumaun Himalaya. The tribal inhabitants of Himalaya use the plant for curing diabetes and abdominal pain of peptic ulcers. The leaves of the plant were collected from Tarai regions of Himalaya. About 2 kg dried and powdered sample of the leaves was extracted with 50% aqueous methanol and extract obtained was concentrated under...

BACKGROUND Limonium bicolor, a halophytic species, can grow in saline or saline-alkali soil, is well known as a traditional Chinese medicine. Recently it attracted much attention for its treatment for cancer. OBJECTIVE The present study was performed to evaluate this species from the phytochemical standpoint and the possible relationship between the antitumor activity and its natural products...

A multiple cell imaging approach combining immunofluorescence by confocal microscopy, fluorescence spectral analysis by multiphotonic microscopy, and transmission electron microscopy identified the site of accumulation of 4-O-(3-methoxybenzaldehyde) β-d-glucoside, a phenol glucoside massively stockpiled by vanilla fruit. The glucoside is sufficiently abundant to be detected by spectral analysis...

Abstract Launaea nudicaulis (L.) Hook. f., Asteraceae, is a wild plant growing in Egypt, used traditionally for treatment of many diseases. LC-HRMS analysis different polarity soluble extracts allowed the annotation fifteen compounds: three alkaloids, four flavonoids, phenolic acids, coumarins, one sphingolipid, and triterpene. Chemical investigation led to isolation identification caffeic acid...

Glycosidically bound compounds have been identified in a vast number of fruits. They have been extensively studied in the cases of grapes and wines (Williams et al., 1980, 1982 a, b; Strauss et al., 1988; Gunata et al., 1990 a, b; Roscher, Winterhalter, 1993; Baumes et al., 1994; Sefton et al., 1994) and for other fruits such as mangoes (Adedeji et al., 1992), peaches (Krammer et al., 1991; Sum...

Blueberries are particularly rich in anthocyanins and favored extensively for their health benefits. In this study, the anthocyanin profiles of fruits four blueberry cultivars (Gardenblue, Legacy, Misty, Brightwell) were investigated. Total content gradually increased all during development, but mature Brightwell Gardenblue had a higher than those Legacy Misty. Thirty-two kinds quantified using...

To obtain immunomodulating substances from Amazonian medicinal plants, hot water extracts from 21 samples available commercially were tested in terms of mitogenic and colony-stimulating factor (CSF)-inducing activities. Among them, Dalbergia monetaria exhibited the highest CSF-inducing activity. Orobol 8-C-glucoside (OCG-8) and orobol 6-C-glucoside (OCG-6) were isolated from the bark of D. mone...