The question of long-range allosteric transitions of DNA secondary structure and their possible involvement in transcriptional activation is discussed in the light of new results. A variety of recent evidence strongly supports a fluctuating long-range description of DNA secondary structure. Balanced equilibria between two or more different secondary structures, and the occurrence of very large ...

bendway weirs are an important tool in multi-purpose erosion control and are implemented to control erosion, restore streams, and improve habitat. these structures create a hydraulic effect that reduces erosion on the outer bank of a bend by reducing flow velocities near the outer bank and reduce the concentration of currents on the outer bank creating better current alignment through the bend....

DNA bending is significant for various DNA functions in the cell. Here, we demonstrate that pseudocomplementary peptide nucleic acids (pcPNAs) represent a class of versatile, sequence-specific DNA-bending agents. The occurrence of anisotropic DNA bends induced by pcPNAs is shown by gel electrophoretic phasing analysis. The magnitude of DNA bending is determined by circular permutation assay and...

Fibre metal laminates (FMLs) have appeared as the most suitable materials for shipbuilding, aeronautical and aerospace applications due to their superior mechanical properties over traditional materials. In this paper, degradation in flexural and impact properties of glass fibre/epoxy composite (GF/E composite) and stainless steel glass fibre/epoxy fibre metal laminate (SS FML) due to hygrother...

Abstract The complex flow structure in sharp bends may cause a series of water and sediment problems which are great risk to flooding control engineering safety. For this reason, there is significance study the characteristics secondary bends. In article, vorticity longitudinal velocity studied by laboratory experiments theoretical analysis. results showed that two opposite circular currents on...

The feasibility of predicting the fracture behavior of surface cracks from shallow cracked bend specimens was investigated. The material studied was a high-strength steel stress relief embrittled to various levels of Charpy-V notch impact toughness. Material toughness was quantified in terms of the J-intergral at total specimen failure (-/„,,), using both deeply notched and shallow-notched bend...

Ebolavirus (Ebov), an enveloped virus of the family Filoviridae, causes hemorrhagic fever in humans and nonhuman primates. The viral glycoprotein (GP) is solely responsible for virus-host membrane fusion, but how it does so remains elusive. Fusion occurs after virions reach an endosomal compartment where GP is proteolytically primed by cathepsins. Fusion by primed GP is governed by an internal ...