Acitretin, a beneficial retinoid, was shown to undergo constant structural interconversions among its geometrical isomers (all-trans-acitretin, 9-cis-acitretin, 13-cis-acitretin, 9, 13-di-cis-acitretin, etc.) by photoisomerization under natural light. The photoisomerization was zero order reaction with an apparent velocity of 4x107 M/min under illumination by white fluorescent lamps (1, 200 lx)...

BACKGROUND Cisplatin (Cis) is one of the most commonly used antineoplastic drugs. It is used as chemotherapy for many solid organ malignancies such as brain, neck, male and female urogenital, vesical and pulmonary cancers. Infliximab blocks tumor necrosis factor alpha (TNF-α). Several studies have reported that infliximab ameliorates cell damage by reducing cytokine levels. AIMS We aimed to i...

From evidence obtained by nuclear magnetic resonance, mass and infrared spectrometry, and chemical techniques, these compounds were identified as cis-4-decene-1, lodioic, cis,cis-4,7-decadiene-1, IO-dioic, cis-4-octene-1,8dioic, glutaric, and adipic acids, N-isovalerylglycine, and N-(methylenecyclopropyl)acetylglycine. (2 KE JOME JH YL ENE CYCLOPROP YL PROPIONiC CH =C8HCH 3 D COCOOH ACID / KMCP...

From evidence obtained by nuclear magnetic resonance, mass and infrared spectrometry, and chemical techniques, these compounds were identified as cis-4-decene-1, lodioic, cis,cis-4,7-decadiene-1, IO-dioic, cis-4-octene-1,8dioic, glutaric, and adipic acids, N-isovalerylglycine, and N-(methylenecyclopropyl)acetylglycine. (2 KE JOME JH YL ENE CYCLOPROP YL PROPIONiC CH =C8HCH 3 D COCOOH ACID / KMCP...

1. Oral administration of trans- and cis-2-methyldecalin to rabbits increased the urinary glucuronide content. 2. The metabolite of the trans isomer was isolated and shown to be either trans-cis-6- or -7-methyl-2-decalol. The metabolite of the cis isomer was shown to be a 1:1 mixture of cis-6-methyl-2-decalol and cis-7-methyl-2-decalols, but the conformations of the hydroxyl groups were not det...

AIMS To isolate predominant ruminal bacteria that produce trans-10, cis-12 conjugated linoleic acid (CLA) from linoleic acid (LA). METHODS AND RESULTS Mixed bacteria from ruminal contents of a cow fed grain were enriched with DL-lactate and trypticase. They produced more trans-10, cis-12 CLA than those that were not enriched (7 vs 2 microg mg protein(-1), P < 0.05). Enrichments had an abundan...