Aim: 10 eyes of 10 patients are reported where progression of keratoconus in the host cornea occurred more than 10 years after penetrating keratoplasty with resultant increase in astigmatism. The technique and results of graft refractive surgery in seven eyes are presented. Methods: The clinical features and management of these patients were retrospectively analysed. Graft refractive surgery in...

Herpes simplex virus-1 (HSV-1) infection of the cornea leads to a potentially blinding condition termed herpetic stromal keratitis (HSK). Clinical studies have indicated that disease is primarily associated with recurrent HSK following reactivation of a latent viral infection of the trigeminal ganglia. One of the key factors that limit inflammation of the cornea is the expression of Fas ligand ...

PURPOSE Tenascin (TN) is a large hexameric extracellular matrix glycoprotein that is expressed in developing organs and tumors. It has also been reported that TN is expressed in the embryonic cornea and during corneal wound healing. However, the role of TN in the cornea is not fully known. In this study, the role of TN in corneal wound healing was examined using the TN knockout (KO) mouse. ME...

AIM 10 eyes of 10 patients are reported where progression of keratoconus in the host cornea occurred more than 10 years after penetrating keratoplasty with resultant increase in astigmatism. The technique and results of graft refractive surgery in seven eyes are presented. METHODS The clinical features and management of these patients were retrospectively analysed. Graft refractive surgery in...

Background. To investigate the correlation between corneal biomechanics and the surgically induced corneal high-order aberrations (HOAs) after small incision lenticule extraction (SMILE) and femtosecond laser in situ keratomileusis (FS-LASIK). Methods. A total of 150 right myopic eyes that underwent SMILE or FS-LASIK surgery were included in this retrospective study, 75 eyes in each group. The ...

PURPOSE To describe the technique of limbal stem cell-sparing corneoscleroplasty for the management of advanced keratoglobus. METHODS A patient with bilateral advanced keratoglobus, with best-corrected visual acuity of 20/400 in the right eye and 20/200 in the left eye, underwent limbal stem cell-sparing corneoscleroplasty of the right eye. Initially, a 360-degree limbal incision with 200-μm ...

.he cornea performs its main optical function not directly by cellular activity but by the physicochemical arrangement of its inert collagen and mucopolysaccharides. The swelling of the ground substance largely determines whether the collagen fibrils are in their normal lattice arrangement, transparent to light, or whether this delicate alignment is distorted. Ultimately, the movement of water ...

(2) The angle made by the blade with the surface of the globe, i.e., the degree of obliquity of the incision. From the same external site an incision perpendicular to the scleral surface may penetrate the ciliary body, whereas a slanting incision parallel to the iris surface would enter the anterior chamber (Swan, 1959). Much controversy still exists concerning some of the external landmarks of...