objectives: the onset of multiple sclerosis in the majority of the cases occurs as a clinically isolated syndrome (cis). we sought to assess serum levels of 25-hydroxyvitamin d (25-ohd) in cis patients and healthy controls. methods: in this cross-sectional study 40 patients (36 women and 4 men) with cis manifesting as a single isolated optic neuritis and 40 age- and sex-matched healthy controls...

Multiple sclerosis (MS) is a neurological autoimmune disease that affects nearly 100,000 Canadians between the ages of 20 and 49 [1]. The damages myelin, protective layer surrounding nerves, which causes irreversible damage to central nervous system (CNS) Common symptoms for patients with MS include vision impairment, loss coordination, cognitive impairment. As 2015, life expectancy approximate...