Although pheochromocytoma occurs in 1% of patients with von Recklinghausen's disease, composite tumors in this syndrome are much rarer, with isolated case reports in the literature. Most gastrointestinal stromal tumors (GISTs) are solitary and sporadic. Multiple GISTs however, are associated with clinical syndromes particularly von Recklinghausen's disease. We believe this is the first report o...

A 16-year-old girl presented with symptomatic symmetrically enlarged butterfly-shaped Grade III (4.1–6 cm, measured from the hymen to distal edge (cranial/caudal)-BCD [1] (‘B’ – Cosmetic bother, ‘C’ –Clitoral hood involvement, ‘D’ –Dyspareunia due labia minora or Discomfort physical activity) of 4 years duration. She was a virgointacta, hence activity. had an uncomplicated surgical reduction di...

A two-year-and-eight-month-old girl presented with clitoromegaly and short stature. Two cell lines, 45,X and 46,X,idic(Y)(q11.2), were observed. Cytogenetic and fluorescence in situ hybridisation investigations were carried out on her peripheral lymphocytes and gonadal cells, to determine the genotype-phenotype effect with respect to differential tissue distribution, effects of the sex determin...

Isolated involvement of the clitoris by vascular malformation (VM) is very rare. Clinically, the lesion simulates female pseudohermaphroditism. A five-year-old girl presented with clitoromegaly and a clinical diagnosis of solitary VM of the clitoris was made. Magnetic resonance imaging showed characteristic features and confirmed the diagnosis and the extent of the VM. This is the first reporte...

INTRODUCTION Persistent sexual arousal disorder (PSAS) is a poorly documented condition characterized by persistent genital arousal in the absence of conscious feelings of sexual desire. AIM To determine whether there are replicable features associated with PSAS, to describe salient characteristics of women reporting this condition, and to determine predictors of distress. METHODS A 46-item...

OBJECTIVE To investigate sexual function in women with complete androgen insensitivity syndrome (CAIS) and to investigate the prevalence of factors that might contribute to sexual difficulties. DESIGN Cross sectional survey and clinical examination. SETTING Tertiary hospital multidisciplinary intersex clinic and an international peer support group for CAIS. PATIENT(S) Sixty-six adult wome...

PURPOSE We defined basic guidelines for transcutaneous mechanical nerve stimulation in modifying pelvic floor responses in women and determined the efficacy of transcutaneous mechanical nerve stimulation in treating stress urinary incontinence. MATERIALS AND METHODS Perineal and clitoral transcutaneous mechanical nerve stimulation was performed in healthy volunteers while measuring changes in...