Background & Aims: This study was performed to compare the effects of open and closed chain terminal knee extension exercises on onset latency of vastus medialis obliques (VMO) and vastus lateralis (VL), pain and function in subjects diagnosed with patellofemoral pain syndrome (PFPS). Methods: In a pretest and posttest 5-week intervention study, 26 subjects diagnosed with PFPS and 13 healthy su...

Sequenced physiologic muscle activations in the upper and lower extremity result in an integrated biomechanical task. This sequencing is known as the kinetic chain, and, in upper extremity dominant tasks, the energy development and output follows a proximal to distal sequencing. Impairment of one or more kinetic chain links can create dysfunctional biomechanical output leading to pain and/or in...

design of a logistics network in proper way provides a proper platform for efficient and effective supply chain management. this paper studies a multi-period, multi echelon and multi-product integrated forward-reverse logistics network under uncertainty. first, an efficient complex mixed-integer linear programming (milp) model by considering some real-world assumptions is developed for the inte...

in this research, we address the application of uncertaintyprogramming to design a multi-site, multi-product, multi-period,closed-loop supply chain (clsc) network. in order to make theresults of this article more realistic, a clsc for a case study inthe iron and steel industry has been explored. the presentedsupply chain covers three objective functions: maximization ofprofit, minimization of n...

Thermodynamic properties and detailed chemical kinetic models have been developed for the combustion of two oxygenates: methyl butanoate, a model compound for biodiesel fuels, and methyl formate, a related simpler molecule. Bond additivity methods and rules for estimating kinetic parameters were adopted from hydrocarbon combustion and extended. The resulting mechanisms have been tested against ...

In a global economy, an efficient supply chain as a main core competency empowers enterprises to provide products or services at the right time in the right quantity, at a low cost. This paper is to plan a single product, multi-echelon, multi-period closed loop supply chain for high-tech products (which have continuous price decrease). Ultimately, considering components rated to procurement, pr...

Mechanisms for the Ca2+-dependent gating of single large-conductance Ca2+-activated K+ channels from cultured rat skeletal muscle were developed using two-dimensional analysis of single-channel currents recorded with the patch clamp technique. To extract and display the essential kinetic information, the kinetic structure, from the single channel currents, adjacent open and closed intervals wer...

Background The aim of this study was to asses results obtained from a range of commonly performed lower extremity “open and closed” chain kinetic tests used for predicting foot function and correlate these test findings to data obtained from the Zebris WinFDM-T system. When performed correctly these tests are thought to be indicators of lower extremity function. Podiatrists frequently perform e...