BACKGROUND Despite significant advances in unravelling the pathophysiology of cluster headache (CH), little is known about neuropsychological functioning. Apart from neuroimaging studies indicating involvement of posterior hypothalamic and other areas frequently involved in nociception, some studies suggest involvement of prefrontal areas. Among others, these mediate executive functioning (EF)....

Growth hormone and prolactin levels and their response to various stimuli were studied in patients with cluster headache. All the endocrine responses evaluated were normal.

Active myofascial trigger points (MTrPs) have been found to contribute to chronic tension-type headache and migraine. The purpose of this case series was to examine if active trigger points (TrPs) provoking cluster-type referred pain could be found in cluster headache patients and, if so, to evaluate the effectiveness of active TrPs anaesthetic injections both in the acute and preventive headac...

BACKGROUND Existing criteria for the diagnosis of headache do not indicate which clinical features are most important to establish or exclude primary headache diagnoses. OBJECTIVE To determine the value of history taking in the evaluation of patients with primary headache syndromes. METHODS A MEDLINE search of English-language studies published since 1966 and a hand search of bibliographies...

Most idiopathic headache syndromes are still recognized as vascular headaches although the clinical picture points towards a central triggering cause. The early functional imaging work using PET shed light on the genesis of some syndromes, implying that the observed activation in migraine (brainstem) and in cluster headache (hypothalamic grey) is involved in the pain process in a permissive or ...

Pharmacological preparations of cannabinoid compounds have a variety of therapeutic uses in medicine, including different pain syndromes, but have not been previously reported as beneficial for cluster headache. We present a patient with cluster headache who was refractory to multiple acute and preventive medications but successfully aborted his attacks with recreational marijuana use; subseque...

Effective occipital nerve stimulation during pregnancy in a cluster headache patient Dear Editor, Cluster headache is a rare primary headache disorder characterized by attacks of excruciating, intermit-ting short-lasting unilateral temporal or orbital pain (1). Cluster headache in pregnancy can be difficult to treat because of a limitation in treatment options. The only acute treatment that is ...

OBJECTIVE To understand the mechanism of action of oxygen treatment in cluster headache. BACKGROUND Trigeminal autonomic cephalalgias, including cluster headache, are characterized by unilateral head pain in association with ipsilateral cranial autonomic features. They are believed to involve activation of the trigeminovascular system and the parasympathetic outflow to the cranial vasculature...