PURPOSE The aim of this study was to explore the risk factors, clinical symptoms, hematological parameters, causative pathogen and antibiotic susceptibility of neonatal sepsis in a Chinese NICU. METHODS A retrospective survey was conducted on 116 cases of neonatal sepsis in NICU at the Maternal and Child Care Hospital in Shenzhen, China from January 2009 to December 2012. Patients were divide...

Bacterial pathogens are becoming more and more resistant to antibiotics used commonly by healthcare practitioners. Despite introduction of new antibiotics, empiric treatment of patients with bloodstream infections (BSIs) became a major challenge for practicing physicians.1,2 To depict the susceptibility patterns of BSI pathogens endemic in a referral pediatric hospital, Children’s Medical Cente...

OBJECTIVES Methicillin resistance in Staphylococcus aureus and coagulase-negative staphylococci (CoNS) is caused by expression of the low-affinity penicillin-binding protein (PBP) 2a encoded by the mecA gene. This gene is carried on the staphylococcal cassette chromosome mec (SCCmec) of which several types and subtypes have been described. CoNS and S. aureus share SCCmec types and it has been s...

We investigated the nature of the staphylococcal cassette chromosome mec (SCCmec) elements and cognate insertion sites in a collection of 42 clinical staphylococcal isolates of various species from Norway. The ccr and mec genes and the attachment sites (attL/attR) were identified by PCR, Southern blot hybridization, and DNA sequencing. We found 10 possibly new SCCmec types and one previously un...

OBJECTIVE To determine the incidence of Coagulase- negative S. aureusin urinary tract infections and sensitivities of these isolates to antimicrobial agents. STUDY DESIGN Cohort study. PLACE AND DURATION OF STUDY Dr. Essa Laboratory and Immunology and Infectious Disease Research Laboratory (IIDRL), Microbiology Department, University of Karachi, from January 2009 to January 2010. METHODOL...

BACKGROUND Coagulase-negative staphylococci (CoNS) are the most common bovine mastitis causing bacteria in many countries. It is known that resistance for antimicrobials is in general more common in CoNS than in Staphylococcus aureus but little is known about the antimicrobial resistance of specific CoNS species. In this study, 400 CoNS isolates from bovine mastitic milk samples were identified...

BACKGROUND Coagulase negative Staphylococci (CoNS) are one of the most common bacteria found on human skin and on mucous membranes as a component of normal flora. The presence of CoNS in clinical specimens is frequently associated with an infectious aetiology or contamination. OBJECTIVES We aimed to evaluate CoNS species distribution and susceptibility patterns in specimens obtained from clin...

given the inappropriate use of antibiotics and prevalence of resistant bacteria, there is urgentneed for antibacterial drugs that have fewer side effects than antibiotics. satureja bachtiaricais a medicinal plant which had many uses in traditional medicine. in this research, the ethanolextract of leave of satureja bachtiarica is tested on coagulase-negative staphylococcus strains.materials and ...

Gram positive pathogens mainly Staphylococcus aureus, Enterococcus and Coagulase Negative Staphylococcus are hospital acquired (HA) pathogens. HA strains are usually multidrug resistant (MDR). Monitoring of these strains is essential in order to control their spread in the hospital environment and transmission to the community. The objectives were to assess the prevalence of Gram positive patho...

Recent reports associate Staphylococcus lugdunensis with severe infection in humans. The frequency of this microorganism in urine cultures is unknown. Five hundred isolates of coagulase-negative staphylococci (CoNS) were recovered from 4,652 consecutive urine specimens submitted for culture to the Mayo Clinic Microbiology Laboratory. Thirty-one (6%) of 500 isolates of CoNS were identified as S....