Magnetic nanoparticles (MNPs) are of high interest due to their application in medical fields, in particular for theranostics. Specific properties required for such particles include high magnetization, appropriate size and stability. Biocompatible magnetically soft magnetite particles (Fe3O4) have been investigated for biological purposes. The intrinsic instability of these nanoparticles and t...

In the field of vascular gene therapy, targeting systems are promising advancements to improve site-specificity of gene delivery. Here, we studied whether incorporation of magnetic nanoparticles (MNP) with different magnetic properties into ultrasound sensitive microbubbles may represent an efficient way to enable gene targeting in the vascular system after systemic application. Thus, we associ...

In this study, the interaction of DMSA-coated magnetite nanoparticles (5 and 10 nm core-size) with Saccharomyces cerevisae was investigated using magnetic resonance (MR) and transmission electron microscopy (TEM). The TEM micrographs revealed magnetite nanoparticles attached externally to the cell wall. The MR data support the strong interaction among the nanoparticles supported by the cells. A...

Iron oxide nanoparticles are used for contrast enhancement in magnetic resonance imaging (MRI). We have prepared gold-coated iron oxide nanoparticles that show no change in their superparamagnetic behavior as a consequence of coating. Their potential use as MRI contrast agents was investigated by monitoring their T2 relaxation time with concentration. Cytotoxicity of these nanoparticles was als...

We report in vitro and in vivo magnetic resonance (MR) imaging of C6 glioma cells with a novel acetylated 3-aminopropyltrimethoxysilane (APTS)-coated iron oxide nanoparticles (Fe3O4 NPs). In the present study, APTS-coated Fe3O4 NPs were formed via a one-step hydrothermal approach and then chemically modified with acetic anhydride to generate surface charge-neutralized NPs. Prussian blue stainin...

a novel magnetic mixed hemimicell solid phase extraction (mmhspe) technique for speciation analysis of soluble, ferrous and ferric iron in legumes sample by flame atomic absorption spectrometry analysis (faas) was developed. mmhspe system consisting of alumina-coated magnetite nanoparticles (fe3o4/al2o3nps) modified by sodium dodecylsulfate-1-(2-pyridylazo)-2-naphthol (sds-pan) have been succes...

This thesis deals with the synthesis, characterisation, and some applications of ferrimagnetic iron oxide nanoparticles. The iron oxide systems presented in this work are Fe3O4, γ-Fe2O3, NixFe3−xO4, CoxFe3−xO4. Iron oxide nanoparticles were prepared using chemical synthesis methods. Nanoparticles with a narrow size distribution were synthesised using zone confinement methods such as nanoemulsio...

An electrochemical mass sensor for clinically relevant detection of insulin in human serum conjugated to magnetic nanoparticles and captured onto antibody immobilized gold coated quartz resonators is reported for the first time.

Objective(s): According to the unique properties of magnetic nanoparticles, their usages in medicine and industry have increased in the last decade. Due to the vital role of liver in the body, the accumulation of CoFe2O4 and CoFe2O4@DMSA was studied. Materials and Methods:The nanoparticles were synthesized by co-precipitation method and were coated with DMSA. The techniques XRD, TEM, DLS, FTIR,...

In this article, we report the magnetic properties of surfactant coated g-Fe2O3 nanoparticles which are pressed under different pressures. With increasing pressure, the sample volume decreases, density increases, and a 55% density change has been achieved. The blocking temperature is increased from 50 to 80 K. Analyzing the data of blocking temperature versus densities, which exhibits linear re...