AIMS To determine the frequency of abnormal pancreolauryl tests in untreated and treated adults with coeliac disease and to see whether abnormalities in treated coeliac patients correlate with the degree of recovery of intestinal morphology or brush border enzyme activity. METHODS Pancreolauryl tests were performed in a study population of 57 adult coeliac patients (25 on gluten containing di...

Immunoregulatory cells were enumerated in 19 coeliac disease children on a gluten free diet by means of monoclonal antibodies that define total T lymphocytes (T3), helper/inducer T cells (T4), suppressor/cytotoxic T cells (T8) and monocytes (M1), as well as by means of surface receptors for Fc fragments of IgM and IgG (T mu and T gamma, respectively). In addition, suppressor cell function was a...

BACKGROUND Coeliac disease is an immune-mediated enteropathology triggered by the ingestion of cereal gluten proteins. This disorder is associated with imbalances in the composition of the gut microbiota that could be involved in its pathogenesis. The aim of the present study was to determine whether intestinal Enterobacteriaceae populations of active and non-active coeliac patients and healthy...

In recent years, you have likely heard that some people are eating gluten-free foods. Have ever wondered why? Coeliac disease is one of the main reasons for this dietary choice. It affects all ages from around world. a genetic disorder causes inflammation in intestines and results various symptoms can be observed other parts body. Unfortunately, often ignore coeliac or treat it like simple alle...

BACKGROUND Up to 1% of the population suffer from coeliac disease. Data on the prevalence in elderly people is scant. We hypothesized that they would over time have developed obvious symptoms. Clinically silent or undiagnosed disease would thus be relatively uncommon. AIMS To evaluate the prevalence of coeliac disease in elderly people. METHODS The study comprised 2815 individuals aged 52-7...

LETTERS Invasive or non-invasive methods for the diagnosis of subclinical coeliac disease? I read with great interest the letters published in Gut on the role of small bowel biopsies and antiendomysial antibodies (EMA) as methods for diagnosing coeliac disease in patients with iron deficiency anaemia (IDA) (Gut 2001;49:595). In particular, Pearce et al seem to prefer EMA instead of histological...

O n the basis of screening studies on healthy volunteers, coeliac disease is now recognised to affect 1% of the population. The current optimal serological testing for coeliac disease may be immunoglobin (Ig)A endomysial, IgA tissue transglutaminase or a combination of the two, with a positive predictive value in excess of 95% provided IgA deficiency is excluded. Patients with positive serology...

Fifty patients presenting sequentially with a history of recurrent aphthae were investigated for evidence of nutritional deficiencies and coeliac disease. In the group, two patients were found to have coeliac disease and their recurrent aphthae cleared soon after starting a gluten free diet. This study confirms the presence of an increased prevalence of nutritional deficiency and of coeliac dis...

It is uncertain whether coeliac node metastasis precludes long-term survival in distal oesophageal cancer. This nationwide population-based cohort study included patients who underwent surgical resection for stage III or IV distal oesophageal cancer in 1987-2010 with follow-up until 2014. A minority (17.0%) had neoadjuvant therapy. The prognosis in patients with coeliac node metastasis was comp...

Background Coeliac disease is a chronic enteropathy that remains a challenge for the clinician, due to its atypical manifestations and etiopathogenic complexity. Objective This article intends to describe the oral characteristics of Coeliac Disease in children in order to facilitate their management in the dental office. Methods A review of the literature was performed electronically in Pub...