OBJECTIVE Coagulopathy is a complication of traumatic brain injury and its presence after injury has been identified as a risk factor for prognosis. It was our aim to determine whether neurologic findings reflected by Glasgow Coma Scale at initial resuscitation can predict hemocoagulative disorders resulting from traumatic brain injury that may aggravate clinical sequelae and outcome in childre...

High-dose intravenous thyroxine (T4) is the preferable treatment for myxedema coma. We describe the clinical course of a 69-year-old man who presented with myxedema coma and received oral levothyroxine (LT4) therapy (1 mg) in a split dose. This suggests split high-dose oral LT4 as a therapeutic option in myxedema coma.

The schema and ontology matching systems COMA and COMA++ are widely used in the community as a basis for comparison of new match approaches. We give an overview of the evolution of COMA during the last decade. In particular we discuss lessons learned on strong points and remaining weaknesses. Furthermore, we outline the design and functionality of the upcoming COMA3.0.