OBJECTIVE To see the characteristics, course and outcome of patients suffering from intracranial tuberculoma. METHODS Retrospective review of 102 patients diagnosed as intracranial tuberculoma at a tertiary care center over 10 years. RESULTS A total of 102 cases were seen with an age range of 1 to 75 years (mean, 30 years). Predisposing factors included Diabetes mellitus (8 patients) and pr...

Hypoglycaemia remains a serious and much feared complication of insulin therapy. In this study, patients attending an accident and emergency department in hypoglycaemic coma were randomized to treatment with either intravenous dextrose (25g) or intramuscular glucagon (1mg), administered into the right thigh. Restoration of normal conscious level was slower after glucagon than dextrose (9.0 vs 3...

To determine the factors affecting the outcome of patients with traumatic acute subdural hematoma, we reviewed the records of7 4 consecutive comatose patients with a Glascow coma scale Score (GCS) of less than 8 who had been admitted to Imam Hosein Medical Center from 1990 to 1996 and had undergone a uniform treatment protocol. The overall mortality rate was 73% and 23% had functional reco...

OBJECTIVE In bacterial meningitis, a decreased level of consciousness is predictive for unfavorable outcome, but the clinical features and outcome in patients presenting with a minimal score on the Glasgow Coma Scale are unknown. METHODS We assessed the incidence, clinical characteristics, and outcome of patients with bacterial meningitis presenting with a minimal score on the Glasgow Coma Sc...

Coma, vegetative state (VS) and minimally conscious state (MCS) are disastrous outcomes following severe traumatic brain injury. Due to the extent of the resultant neurological deficits including hemisphere damage, loss of cellular integrity, altered and abnormal movements such as flexor and extensor patterns, and alterations in cranial nerve function, it can become difficult for the interprofe...

Thirty-eight patients in coma due to head trauma, cerebrovascular accidents, hypoxia, hypoglycaemia, or barbiturate intoxication, and 15 cases of brain death were studied. Cerebral metabolic rate of oxygen (CMRO(2)) was obtained from the arteriovenous oxygen difference and cerebral blood flow (CBF) measured by intra-arterial (133)Xenon method. If hypothermia and CNS depressants were excluded, C...

BACKGROUND In India, tuberculous meningitis (TBM) is still a major cause of neurological disabilities and death. AIM To identify the clinical variables which predict the outcome in childhood TBM. SETTING Tertiary teaching hospital. DESIGN Prospective observational study. MATERIALS AND METHODS Thirty-six clinical variables were analyzed in 123 consecutive children with TBM admitted betwe...

Environmental temperature is one of the most important abiotic factors affecting insect behaviour; virtually all physiological processes, including those which regulate nervous system function, are affected. At both low and high temperature extremes insects enter a coma during which individuals do not display behaviour and are unresponsive to stimulation. We investigated neurophysiological corr...