Carotid Artery Occlusion Following Ingestion of LSD • A 20-year-old white woman developed a left hemiplegia following the ingestion of LSD. Initial angiography revealed marked constriction of the internal carotid artery at the level of the siphon which, in a few days, was converted to occlusion of the carotid artery at that level. It is suggested that LSD, an amine derivative of the ergot alkal...

PURPOSE To review patients who have presented with acute strokes from a middle cerebral artery occlusion in whom in addition to the middle cerebral artery thromboembolus, an internal carotid artery occlusion has been present, and in whom angioplasty of these totally occluded internal carotid arteries has bee n successful. METHODS We reviewed retrospectively our experience in treating a cute s...

Alternative to carotid endarterectomy, carotid artery stenting (CAS) can be performed for symptomatic severe stenosis of internal carotid artery, especially for high-risk patients. Among several complications after CAS, subacute in-stent thrombosis is rare but important, because patient's condition can deteriorate rapidly. Subacute in-stent thrombosis with carotid artery occlusion can be manage...

BACKGROUND AND PURPOSE Protein kinase C epsilon (epsilonPKC) has been implicated as a neuroprotectant in vitro. We studied epsilonPKC activation (by its localization and proteolysis) in a rodent stroke model and correlated the effects of hypothermia with epsilonPKC activity after cerebral ischemia. METHODS Rats were subjected to permanent distal middle cerebral artery occlusion plus 1 hour of...

The role of the carotid sinus reflex in control of the blood flow in the left circumflex coronary artery was studied in nine open-chest dogs anesthetized with chloralose. Flow was measured with an electromagnetic flowmeter. The effects of bilateral common carotid occlusion were examined in a three-part experiment in each dog. (1) Under vagotomy (control) conditions, occlusion of both common car...

Eighty-four patients with cerebroTucnlar disease were studied by cerebral angiograpby and a prototype Doppler device, ultrasonic quantitative flow measurement (UQFM), that provides data from which absolute common carotid flow can be determined. The UQFM showed significantly lower flows in 23 patients who had complete occlusion of the internal carotid artery on the affected side (p < 0.001). In ...