Neutrophils play a crucial early role during the innate response, but little is known about their possible contribution when an adaptive immune response is installed. A robust neutrophilia and a T helper 1 (Th1) immune response are present after immunization with Complete Freund Adjuvant (CFA). We show that when FITC-labeled OVA was injected into the footpad of OVA/CFA immunized mice, the main ...

The stepping forces of normal and Freund Complete Adjuvant (FCA)-induced arthritic rats were studied in vivo using a proposed novel analgesic meter. An infrared charge-coupled device (CCD) camera and a data acquisition system were incorporated into the analgesic meter to determine and measure the weight of loads on the right hind paw before and after induction of arthritis by FCA injection into...

In order to replace the use of mammals for the production of hyperimmune sera and to replace Freund"s complete adjuvant (FCA) with its undesirable side effects, the production and immunological features of IgY were investigated systematically. An important advantage of IgY is that large amounts can easily be extracted from the yolk of immunized laying hens. With special regard to animal welfare...

Muramyl dipeptide, N-acetylmuramyl-L-alanyl-D-isoglutamine, induced adjuvant arthritis in WKA rats when injected in a water-in-oil emulsion prepared with Freund incomplete adjuvant (Difco), but not when emulsified with Drackeol and Arlacel A.

Neutrophils play a crucial early role during the innate response, but little is known about their possible contribution when an adaptive immune response is installed. A robust neutrophilia and a T helper 1 (Th1) immune response are present after immunization with Complete Freund Adjuvant (CFA). We show that when FITC-labeled OVA was injected into the footpad of OVA/CFA immunized mice, the main ...

A chemically synthesized copy (S-CB7) of a fragment (35 amino acid residues) of type 24 streptococcal M protein was covalently linked to polylysine with carbodiimide and injected subcutaneously into rabbits without adjuvant. Although the primary immune responses as measured by enzyme-linked immunosorbent assays at biweekly intervals were weak, the secondary responses as measured by both enzyme-...

Given an H-polytope P and a V-polytope Q, the decision problem whether P is contained in Q is co-NP-complete. This hardness remains if P is restricted to be a standard cube and Q is restricted to be the affine image of a cross polytope. While this hardness classification by Freund and Orlin dates back to 1985, there seems to be only limited progress on that problem so far. Based on a formulatio...

Avian vitellin antibodies (IgY) obtained after immunization with mouse IgG and mouse IgM in the presence or absence of Freund"s complete adjuvant are suited for labelling with FITC or biotin. In FACS analysis the antibodies prove to be excellent tools in detecting mouse monoclonal antibodies of different isotypes. The working dilution (titer of IgY-FITC) is highest when egg preparations of the ...

We give a complete treatment of factorisation of Deeply Virtual Compton Scattering (DVCS) in the generalised Bjorken limit, using the local Operator Product Expansion (OPE). The method allows a straightforward proof that, at leading twist, the DVCS amplitude factorises into an integral over coefficient functions and Skewed Parton Distribution Functions (SPDFs). The integral is well defined for ...

Gauge functions significantly generalize the notion of a norm, and gauge optimization, as defined by [R. M. Freund, Math. Programming, 38 (1987), pp. 47–67], seeks the element of a convex set that is minimal with respect to a gauge function. This conceptually simple problem can be used to model a remarkable array of useful problems, including a special case of conic optimization, and related pr...