Background: Congenital heart disease is the most common type of maternal abnormality and is the leading cause of mortality in the first year of life. The aim of this study was to determine the epidemiological and related factors of congenital heart disease (CHD) in children referred to the pediatric heart clinic of Vali-e-Asr Hospital of Birjand, Iran. <e...

Congenital heart disease (CHD) is present in 0.8% of all live births and is therefore one of the most common congenital malformations (Fyler et al., 1980). The spectrum of congenital heart defects is significantly higher in fetuses than in live born infants because of their reduced viability (Tennstedt et al., 1999). The prognosis of congenital heart disease can be poor; almost one third to one...

OBJECTIVES To investigate hypoxia and sleep disordered breathing in infants with congenital heart disease. METHODS Prospective study. In-hospital full polysomnography was performed on 14 infants with congenital heart disease, age 7 +/-1 months, and in 7 normal infants, age 10 +/-2 months. Congenital heart disease infants were classified as acyanotic (n=7) or cyanotic (n=7). RESULTS Nutritio...

Methods Population-based cohort study using the Quebec Congenital Heart Disease Database of all patients with congenital heart disease coming into contact with the Quebec healthcare system between 1983 and 2005. Subjects with specific diagnoses of congenital heart disease and age 65 years at time of entry into the cohort were followed for up to 15 years. The primary outcome was all-cause mortal...

GENETIC imbalance, the result of aneuploidy or chromosomal structural rearrangements, is now recognized as a cause of anomalous embryogenesis. In general, the anomalies have been extensive and severe when the chromosomal abnormalities have affected segments lengthy enough to be detected by use of currently available techniques. The purposes of the present study were: (1) to determine the incide...

The last 15 years have witnessed a very remarkable change in the attitude of the clinician towards cyanotic congenital heart disease. It is within the memory of many that it was the custom to make a simple diagnosis of congenital heart abnormality with cyanosis, and express the opinion that little or nothing could be done about it. Then there appeared the pioneer work of Abbott and others which...