manufacturing new hepatitis b virus vaccines, specifically by the use of nanoparticles, is of high global interest. in this paper, a new biocompatible and biodegradable structure of nano-sized hepatitis b virus’ surface antigen (hbsag) was generated by conjugation with dendrimers, a low cost biodegradable and biocompatible polymer. the physicochemical properties of the conjugate were characteri...

In [1] (Hybrid Conjugate Gradient Algorithm for Unconstrained Optimization J. Optimization. Theory Appl. 141 (2009) 249 - 264), an efficient hybrid conjugate gradient algorithm, the CCOMB algorithm is proposed for solving unconstrained optimization problems. However, the proof of Theorem 2.1 in [1] is incorrect due to an erroneous inequality which used to indicate the descent property for the s...

accurate calculation of reliability index is very important for the reliability analysis of structures. in some limit state functions with nonlinear characteristic and several local optimum design points, the computational reliability methods may not appropriately determine the failure probability, and iterative reliability approaches may be converged to local optimum design points. in this pap...

[1] Geologic investigations of how the Tibetan plateau is currently deforming have focused primarily on its boundary faults. Consequently, how the interior of the plateau deforms remains poorly understood. To fill this gap in knowledge, we conducted field mapping, analysis of remote sensing and digital topographic data, and reinterpretation of existing geologic maps in central Tibet. This study...