A fast, simple and fully automated RP-HPLC analytical method with UV detection for determination of indomethacin substance and its degradation product 4-chlorobenzoic acid was modified and validated. The analysis was performed at isocratic conditions, applying a mobile phase of acetonitrile and 0.5% ortophosphoric acid (50:50, v/v) at flow rate 1.5 ml/min. The system’s suitability parameters an...

By using the Ward-Takahashi identities in the Landau gauge, we derive exact relations between particle masses and the vacuum expectation value of the Higgs field in the Abelian gauge field theory with a Higgs meson. PACS numbers : 03.70.+k; 11.15-q Despite the pioneering work of ’t Hooft and Veltman on the renormalizability of gauge field theories with a spontaneously broken vacuum symmetry, a ...

Radiation propagating over cosmological distances can probe dark energy. The most probable source of dark energy is a spin-0 field which may be a scalar or a pseudoscalar, changing the dynamical symmetries of electrodynamics. Dark energy as a field predicts spontaneous generation of polarization of electromagnetic waves due to mode mixing. We illustrate this by calculations of propagation in a ...

The present investigation reports the various pharmacokinetic parameters of immediate release aceclofenac tablets incorporating its inclusion complex with hydroxypropyl-β-cyclodextrin. The tablets were prepared using aceclofenac: hydroxypropyl-β-cyclodextrin in a 1:1 molar ratio by the direct compression method (TKN). The results were compared with those of the marketed brand (MKT) and pure dru...

We aimed in this study to describe lamivudine concentration-time courses in treatment-naïve children after once-daily administration, to study the effects of body weight and age on lamivudine pharmacokinetics, and to simulate an optimized administration scheme. For this purpose, lamivudine concentrations were measured in 49 children after at least 2 weeks of didanosine-lamivudine-efavirenz trea...

A semi-analytical method to analyze post-wall waveguides and circuits based on the model of two-dimensional photonic crystals formed by layered periodic arrays of circular cylinders is presented. The propagation constant of the fundamental TE mode, the attenuation constant due to the leakage loss and the effective width of an equivalent rectangular waveguide are calculated. Using the concept of...

I review the recent 5D self-tuning solutions of the cosmological constant problem, and try to unify two cosmological constant problems within the framework of the self-tuning solutions. One problem, the large cosmological constant needed for inflation, is interpreted by starting with the parameters allowing only the dS vacuum, and the vanishing cosmological constant at a true vacuum is realized...

background: breast is one of the main radiological sensitive organs, hence it is important to evaluate absorbed dose to this organ especially to the glandular parts. it is the aim of this study to measure mean glandular dose and image contrast in terms of different mammographic parameters. materials and methods: in this study two mammography machines located at said-al shohada (giotto) and shah...

background: iodine brachytherapy sources with low photon energies have been widely used in treating cancerous tumors. dosimetric parameters of brachytherapy sources should be determined according to aapm tg-43u1 recommendations before clinical use. monte carlo codes are reliable tools in calculation of these parameters for brachytherapy sources. materials and methods: dosimetric parameters (dos...

The problem of self-tuning of coupling parameters in multi-agent systems is considered. Agent dynamics are described by a discrete-time double integrator with unknown input gain. Each agent locally tunes the strength of interaction with neighboring agents by using a normalized gradient algorithm (NGA). The tuning algorithm minimizes the square of the error between an individual agent’s state (v...