Several studies have shown that growth of the primate eye responds in a compensatory direction to both positive and negative spectacle lenses--eyes grow more slowly and become hyperopic in response to positive lenses, and eyes grow more rapidly and become myopic in response to negative lenses. On the other hand, extended wear soft contact lenses, whether positively or negatively powered, induce...

Most contact lens practitioners are dealing with an increasing number of otherwise healthy older (presbyopic) patients. Examination of the literature indicates a persistent theme of age-related change which generally becomes significant after the fourth decade. This review, the second of two parts, documents reported age-related changes in visual acuity, contrast sensitivity, stereoacuity, hype...

Purpose To investigate the correlation between the changes in the ocular surface temperature (OST) and tear film stability over soft contact lenses (SCLs). Methods We enrolled 20 eyes of 20 normal SCL wearers (20 men; 24.4 ± 4.1 years). We used four different daily disposable SCLs: one silicone hydrogel lens (delefilcon A) and three hydrogel lenses (etafilcon A with polyvinylpyrrolidone [PVP]...

PURPOSE To evaluate the performance of two experimental contact lenses (CL) designed to induce relative peripheral myopic defocus in myopic eyes. METHODS Ten right eyes of 10 subjects were fitted with three different CL: a soft experimental lens (ExpSCL), a rigid gas permeable experimental lens (ExpRGP) and a standard RGP lens made of the same material (StdRGP). Central and peripheral refract...

AIMS To describe the fitting of patients with high or irregular astigmatism following penetrating keratoplasty with contact lenses and to answer the question whether or not contact lenses with special back surface design can improve visual acuity in complex cases after penetrating keratoplasty. METHODS 28 eyes were included. They were fitted with contact lenses with a special back surface tha...

The purpose of this study was to investigate the release of the anti-myopia drugs atropine sulfate and pirenzepine dihydrochloride from commercially available soft contact lenses. Standard ultraviolet (UV) absorbance-concentration curves were generated for atropine and pirenzepine. Ten commercially available contact lenses, including four multifocal lenses, were loaded by soaking in atropine or...

Peripheral corneal ulcers can still pose difficult clinical problems despite therapeutic advances such as specific antimicrobial agents, collagenase inhibitors, heparin, ocular lubricants, biological adhesives, and soft contact lenses. This paper reports the healing of several types of progressive marginal ulcers after the excision and recession of adjacent limbal conjunctiva (limbal conjunctiv...

PURPOSE To evaluate changes in the concentration of tear immunoglobulins in contact lens wearers. METHODS A total of 45 cases including 23 contact lens wearers (43 eyes) and 22 age and sex matched healthy controls having no ocular pathology were studied for immunoglobulins (IgA, IgG, IgM) in their tears by single radial immunodiffusion method. RESULTS Most of the cases used soft (56.6%) and...

Wearable contact lenses which can monitor physiological parameters have attracted substantial interests due to the capability of direct detection of biomarkers contained in body fluids. However, previously reported contact lens sensors can only monitor a single analyte at a time. Furthermore, such ocular contact lenses generally obstruct the field of vision of the subject. Here, we developed a ...