Drug delivery from 3-dimensional (3D) structures is a rapidly growing area of research. It is essential to achieve structures wherein drug stability is ensured, the drug loading capacity is appropriate and the desired controlled release profile can be attained. Attention must also be paid to the development of appropriate fabrication machinery that allows 3D drug delivery systems (DDS) to be pr...

22.1 PHYSICOCHEMICAL PROPERTIES OF 22.7 BIODEGRADABLE/ERODIBLE DRUG 22.2 DELIVERY SYSTEMS 22.9 22.2 ROUTES OF DRUG 22.8 OSMOTIC PUMP 22.10 ADMINISTRATION 22.3 22.9 ION EXCHANGE RESINS 22.11 22.3 PHARMACOLOGICAL AND 22.10 NEW MACROMOLECULAR DELIVERY BIOLOGICAL EFFECTS 22.4 APPROACHES 22.12 22.4 PRODRUG 22.4 22.11 CONCLUSION 22.14 22.5 DIFFUSION-CONTROLLED DELIVERY REFERENCES 22.14 SYSTEMS 22.5 2...

Department of Pharmaceutics, Hindu College of Pharmacy, Guntur, Andhra Pradesh, India. _______________________________________________________________________ ABSTRACT Conventional drug delivery systems have slight control over their drug release and almost no control over the effective concentration at the target site. This kind of dosing pattern may result in constantly changing, unpredictabl...

The performance of regenerated cellulose (RC) films and capsules was investigated for their applications in oral controlled drug delivery. Regenerated cellulose films were prepared by non-solvent-mediated, phase inversion of native and depolymerized cotton linter solutions (methylolcellulose; cellulose dissolved in dimethyl sulfoxide/ paraformaldehyde solvent system) in water as well as by phas...

Controlled drug delivery occurs when a polymer is combined with a drug in a such a way that the release profile is predefined. Conventional forms of drug delivery are based on tablets, eye drops, ointments and intravenous solutions. These delivery systems were characterized by an immediate and non controlled kinetics depending essentially on the properties of tissues to absorb drugs.In the last...

Since last three decades delivery of the desired drug as muocoadhesive drug delivery systems has been subject of interest. Mucoadhesion involving a polymeric drug delivery system is a complex phenomenon that includes theory of diffusion, wetting, adsorption, fracture and interpenetration of polymer chains amongst various other processes. Various polymer-based properties such as the degree of cr...

A large number of both natural and synthetic polymers have been studied for powible application in drug delivery. The great advantage of synthetic polymers is their advantageous properties and wide choice availability. Two promising synthetic polymers which have been developed for biomedical applications are polyvinylpyrolidone and polyethylene glycol acrylate based hydrogels. Both of them are ...

A cure for rheumatoid arthritis is yet to be discovered. Although vast resources have been expended in the search for an immunological key to switch off the rheumatoid process, the most significant advances in the treatment of rheumatoid arthritis in recent times had come from gaining better understanding and skill in the safe use of existing disease modifying antirheumatic drugs (DMARDs). If p...

objective(s): ketotifen fumarate (kf) is a selective and noncompetitive histamine antagonist (h1-receptor) that is used topically in the treatment of allergic conditions of rhinitis and conjunctivitis. the aim of this study was to formulate and improve an ophthalmic delivery system of kf.ocular nanoparticles were prepared with the objective of reducing the frequency of administration and obtain...