In the overall long-term management of lead poisoning, chelation therapy can have short-term benefits; however, these benefits must be accompanied by drastic reduction in environmental exposure to lead if therapy is to have any long-term benefit. This discussion is limited to calcium disodium ethylenediaminetetraacetate (CaNa2EDTA), the chelating agent that has been the mainstay of treatment of...

BACKGROUND Previous studies of nickel workers have primarily noted significant early increases in lung and nasal cancers and for various types of accidents. AIMS To examine cancer incidence and mortality, concurrently, for a cohort of male nickel workers at a major nickel and copper producer in Sudbury, Ontario, Canada. METHODS From January 1964 to December 2001, nominal roll and work histo...

the antimicrobial activity of some novel ascorbic acid-metal complexes [bisascorbate complexes of copper (ii), zinc(ii), manganese (11), iron (111), cobalt(ii), lead(ii) and cadmium(ii)] was investigated. four standard strains of bacterial species - staphylococcus aureus, escherichia coli, bacillus subtilis and klebsiella pneumonia and four fungal species - trichophyton sp. penicillium sp., asp...

BACKGROUND Cadmium is a metal used in the zinc, copper and steel industries, and in the manufacture of electric batteries and solar cells. Acute cadmium poisoning is characterized by irritation of the respiratory tract, while in chronic poisoning the main target organ is the renal tubule. AIMS We report a patient with chronic work overexposure to cadmium, who presented a IgA mesangial glomeru...

A i2 inch square plastic bowl some 5 inches deep with sloping ramps has three strands of t inch copper tube fitted around the inside surface, the upper band about 1 inch below the rim, and each 1/16 inch apart A low voltage of 12 to 25 volts is applied to the tapes from a mains transformer or battery. Small animals are attracted up the ramps and into the bowl by a suitable bait; as they cross t...

BACKGROUND Acute poisoning is frequently encountered at emergency department. This study was to investigate the epidemiology and characteristics of patients with acute poisoning who were treated at the Emergency Center, Fujian Provincial Hospital, China. METHODS We retrospectively analyzed the gender, age, causes of poisoning, types of poisons, poisoning route, emergency diagnoses, outcomes, ...

Methanol steam reforming is a promising reaction in terms of hydrogen production for use in PEM fuel cells. Catalyst research has focused mainly on Cu/ZnO formulations, because of their superior selectivity to CO2 and H2. The common byproduct CO is problematic due to its poisoning effect on the anode of a downstream fuel cell. Some years ago it was shown that palladium supported on certain redu...

A group of 39 storage battery workers was evaluated in terms of pertinent biochemical parameters with regard to duration and degree of occupational exposure to lead. Twenty-two of the group had recognized toxic blood lead levels of greater than 60 mcg/100 ml, but fully 31 exceeded the Center for Disease Control's upper limit of normal for erythrocyte protoporphyrin. Other abnormal values found ...

The therapeutic history of sodium diethyldithiocarbamate (dithiocarb) is briefly reviewed. Dithiocarb was discovered serendipitously in our laboratory 35 years ago for the specific treatment of nickel carbonyl poisoning. Since that time, the therapeutic efficacy of dithiocarb has been reported for many disorders, including: nickel, cadmium, thallium, copper, and mercury poisonings, experimental...