Wilson’s disease (WD) is an inherited autosomal recessive disorder that lead to copper accumulation in the liver, brain, cornea, and other organs [1]. WD is treatable by life-long decoppering therapy with the aim of removing excess copper and preventing re-accumulation. This is accomplished with two main groups of drugs: chelating agents, including d-penicillamine (DPA) and trientine, that prom...

Introduction: Copper and zinc play a key role in oxidative reactions and in vivo studies have shown their different effects. In this study we examined the influence of exposure to copper and zinc on catalase and superoxide dismutase (SOD) activities in erythrocytes, total serum antioxidant capacity and malondiadehyde (MDA) production of copper industry workers. Methods: In the present study...

206 2. Day C, McCollum EV. Effect of acute dietary zinc deficiency in rat. Proc Exp Biol Med 1940;45:282-7. 3. Saxena N, Sharma RP, Singh VS. A study of serum zinc and copper levels in psoriasis. Indian J Dermatol Venereol Leprol 1990;56:216-8. 4. McMillan C, Rowe D. Plasma zinc in psoriasis: Relationship to surface area involvement. Br J Dermatol 1983;108:301-5. 5. Portnoy K, Molokhia M. Zinc ...

In plants, copper is an essential micronutrient required for photosynthesis. Two of the most abundant copper proteins, plastocyanin and copper/zinc superoxide dismutase, are found in chloroplasts. Whereas plastocyanin is essential for photo-autotrophic growth, copper/zinc superoxide dismutase is dispensable and in plastids can be replaced by an iron superoxide dismutase when copper is limiting....

The Sorkheh deposit in northwestern Iran exhibits several readily visible general characteristics of sediment-hosted stratiform copper (SSC) mineralization. It consists of fine-grained disseminated base-metal sulfides within gray sandstones (gray beds, the basal whitish Miocene sandstone and shallow-water) that overlie a thick sequence of red beds (Miocene Upper Red Formation). The host gray be...

The Cerattepe (Artvin) mine contains volcanogenic massive sulfide (VMS) deposits in northeastern Turkey. This is a kuroko type deposit located Late Cretaceous volcanic, intrusive and sedimentary rocks, has structure with dense alteration stages. In this study, batch flotation tests were carried out to determine the behavior of new sample (mix ore), that was combination two different ores behavi...

Background: Intra uterine devices (IUDs) are among the most commonly used contraception methods around the world. The most common form of IUDs used in Iran, is IUD Copper T-380A. As recently there is great emphasis on the role of blood zinc levels on general health conditions, this study was performed to assess the effects of IUD T-380-A insertion on zinc and also copper serum levels. Materials...

Zinc and copper were histochemically localized in rat ocular tissues. Zinc was demonstrated by the dithizone method, and copper by the rubeanic acid and rhodanine methods. The retinal photoreceptor's outer segment showed the presence of zinc, but no zinc reaction was seen in other parts of the retina or other ocular tissues, even in rats fed excess zinc. It seems that photoreceptor cells contai...

AIM To assess plasma zinc and copper levels in individuals with anxiety and to test the hypothesis that there is a relationship between copper and zinc concentration and improved symptoms. SUBJECTS AND METHODS Serum from 38 individuals with anxiety and 16 neurotypical age, gender and size similar controls were tested for plasma zinc and copper concentration using inductively-coupled plasma-ma...

BACKGROUND Chronic, excess zinc intake can result in copper deficiency and profound neurologic disease. However, when hyperzincemia is identified, the source often remains elusive. We identified four patients, one previously reported, with various neurologic abnormalities in the setting of hypocupremia and hyperzincemia. Each of these patients wore dentures and used very large amounts of dentur...