نتایج جستجو برای: core max ii

تعداد نتایج: 828116  

2009
Naji M. Najib Isam Salem Nasir M. Idkaidek

The purpose of this study is to investigate the effect of using replicate design on the intra/inter subject variability and bioequivalence of drugs in healthy volunteers. Model drugs used for analysis were amoxicillin/clavulanic acid combination. 24 healthy subjects participated in this study using 4-phase replicate cross over design. Individual disposition kinetic parameters of areas under pla...

2013
K. Großmann U. Frieß E. Peters F. Wittrock J. Lampel S. Yilmaz J. Tschritter R. Sommariva R. von Glasow B. Quack K. Krüger K. Pfeilsticker

A latitudinal cross-section and vertical profiles of iodine monoxide (IO) are reported from the marine boundary layer of the Western Pacific. The measurements were taken using Multi-Axis Differential Optical Absorption Spectroscopy (MAX-DOAS) during the TransBrom cruise of the German research vessel Sonne, which led from Tomakomai, Japan (42 N, 141 E) through the Western Pacific to Townsville, ...

Journal: :Bulletin of the Korean Mathematical Society 2010

Journal: :American journal of physiology. Heart and circulatory physiology 2005
Lie Gao Wei Wang Yu-Long Li Harold D Schultz Dongmei Liu Kurtis G Cornish Irving H Zucker

Chronic heart failure is often associated with sympathoexcitation and blunted arterial baroreflex function. These phenomena have been causally linked to elevated central ANG II mechanisms. Recent studies have shown that NAD(P)H oxidase-derived reactive oxygen species (ROS) are important mediators of ANG II signaling and therefore might play an essential role in these interactions. The aims of t...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2011
Michael Souvatzoglou Gregor Weirich Sarah Schwarzenboeck Tobias Maurer Tibor Schuster Ralph Alexander Bundschuh Matthias Eiber Ken Herrmann Hubert Kuebler Hans Juergen Wester Heinz Hoefler Juergen Gschwend Markus Schwaiger Uwe Treiber Bernd Joachim Krause

PURPOSE To evaluate the dependency of the sensitivity of [(11)C]choline positron emission tomography/computed tomography (PET/CT) for detecting and localizing primary prostate cancer (PCa) on tumor configuration in the histologic specimen. EXPERIMENTAL DESIGN Forty-three patients with biopsy-proven PCa were included. They underwent radical prostatectomy within 31 days after [(11)C]choline PET...

Journal: :Annual review of biochemistry 2003
Stephen T Smale James T Kadonaga

The events leading to transcription of eukaryotic protein-coding genes culminate in the positioning of RNA polymerase II at the correct initiation site. The core promoter, which can extend ~35 bp upstream and/or downstream of this site, plays a central role in regulating initiation. Specific DNA elements within the core promoter bind the factors that nucleate the assembly of a functional preini...

Journal: :Molecular biology and evolution 2011
Susan L Young Daniel Diolaiti Maralice Conacci-Sorrell Iñaki Ruiz-Trillo Robert N Eisenman Nicole King

The origin of metazoans required the evolution of mechanisms for maintaining differentiated cell types within a multicellular individual, in part through spatially differentiated patterns of gene transcription. The unicellular ancestor of metazoans was presumably capable of regulating gene expression temporally in response to changing environmental conditions, and spatial cell differentiation i...

2011
Simon W. Rabkin

To understand the relationship between putative neurohormonal factors operative in hypertension and coronary artery calcification (CAC), the relevant cellular actions of angiotensin (Ang II) and endothelin-1 (ET-1) are reviewed. There is compelling evidence to implicate ET-1 in CAC. ET-1 increases phosphate transport with a 42 to 73% increase in V(max). Increased cellular phosphate may induce C...

Journal: :Frontiers in Materials 2022

Outdoor 24-kV power transmission insulators include two main pieces, namely, the shed and core. In this study, these pieces were manufactured separately by roll/hot pressing hand lay-up methods, respectively. Both core formed from polymer-based composites due to their low weight, high strength-to-weight ratio, higher moisture pollution resistance compared those of ceramic glass sheds. The sheds...

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