IN 1955 one of us (H. E. H.) saw a patient in whom the complaint of haloes arose from deposits in the corneal epithelium resembling those described by Mann (1947) in workers engaged in the manufacture of atebrine. This patient was at that time under treatment for actinic dermatitis with chloroquine and the similarity of the corneal changes to those described by Mann suggested that a relationshi...

Fuchs endothelial dystrophy had DSAEK in the left eye for bullous keratopathy after cataract surgery and trabeculectomy in 1997. Preoperatively, the BSCVA in this eye was 20/200. On the first postoperative day, characteristic interface wavelike deposit accumulation was visualized on slitlamp examination despite corneal edema (Figure 2). A short trial of intensive steroids (from 4 times initiall...

PURPOSE The surgical treatment of band keratopathy usually consists of abrasion of the corneal epithelium followed by removal of the subepithelial calcium deposits by means of an ethylenediamine-tetraacetic acid (EDTA) solution. In order to reduce the discomfort and pain that occur after corneal abrasion, the authors developed a modified technique that avoids the abrasion of the epithelium. M...

A tapetoretinal degeneration combined with a marginal corneal dystrophy was described by Bietti in three patients (two of whom were brothers) in 1937.' The fundus picture was reported to be similar to that of retinitis punctata albescens, but the spots, located mainly at the posterior pole, were refractile, polygonal, and could be seen at all levels of the neuroretina. Pigment changes were seen...

Familial hypercholesterolemia (FH), known to be as the most important cause of severe hypercholesterolemia, is a genetic disease characterized by elevated LDL-Cholesterol (LDL-C), mainly caused by an autosomal dominant condition due to mutations in the LDLR gene that normally encodes the LDL receptor protein, leading to its decreased function and decreased LDL cholesterol clearance from the blo...

Bietti's crystalline dystrophy (BCD) is a rare disease presenting with the appearance of intraretinal crystalline deposits and varying degrees of chorioretinal atrophy commencing at the posterior pole. Within time, intraretinal crystals gradually disappear and chorioretinal atrophy extends beyond the macula even resulting in complete chorioretinal atrophy. Concomitant corneal crystals can be no...