purpose : to report an unusual presentation of chandler syndrome case report : a 22-year-old female came to our clinic with complaint of progressive visual loss in her left eye since three days ago. she had a history of trauma with finger-nail to her left eye eight days ago and had been managed with topical antibiotic. in her examination, the left eye had visual acuity (va) of counting finger a...

Objective: To compare the mean changes in central corneal thickness (CCT) and corneal endothelial-cell density (CED) after removal of silicon oil (ROSO) using anterior (limbal) versus posterior (pars plana) approach in aphakic patients following successful retinal re attachment surgery. Study Design: Randomized controlled trial. Place and Duration of Study: Armed Forces Institute of Ophthalmolo...

BACKGROUND This study aims to present the management and clinical findings of a case of corneal wasp sting and to report the outcome of corneal change and panuveitis after vitrectomy. FINDINGS Clinical findings, anterior segment photographs, corneal endothelial changes, and medical treatment of corneal wasp sting-induced panuveitis are presented. A 95-year-man was stung by a wasp on his left ...

PURPOSE To investigate, after 24 h, the safety of genipin or ultraviolet A (UVA)-riboflavin crosslinking of keratocytes and endothelial cells. METHODS Fifteen New Zealand white rabbits were selected and divided into a PBS group (five rabbits), a 0.2% genipin crosslinking (GP-CXL) group (five rabbits), and a UVA-riboflavin crosslinking (UVA-CXL) group (five rabbits). In the GP-CXL and PBS grou...

PURPOSE To evaluate the clinical aspects of patients with primary cornea guttata and the morphology of their corneal endothelial cells. METHODS Twenty-three patients who visited Kanazawa Medical University Hospital or related hospitals in Ishikawa or Fukui prefectures and were diagnosed as having primary cornea guttata by slit lamp microscopy and contact specular microscopy underwent an analy...

CASE REPORT A 64 year-old female with Parkinson disease treated with amantadine for two years who suddenly suffered bilateral corneal oedema. It was initially treated as herpetic endotheliitis without improvement as we lacked information on her chronic treatment. The corneal oedema finally resolved after withdrawing the drug. DISCUSSION Amantadine hydrochloride may produce endothelial dysfunc...

PURPOSE To evaluate the outcome for scleral fixation of a foldable acrylic intraocular lens (IOL) in aphakic post-pars plana vitrectomy eyes for vitreoretinal disease. METHODS The medical records of 15 patients were reviewed. We evaluated such factors as the underlying vitreoretinal disease, preoperative expected refraction and postoperative actual refraction, best corrected visual acuity (BC...

Corneal transparency is maintained by the corneal endothelium through its pump and barrier function. Severe corneal endothelial damage results in dysregulation of water flow and eventually causes corneal haziness and deterioration of visual function. In 2013, we initiated clinical research of cell-based therapy for treating corneal decompensation. In that study, we removed an 8-mm diameter sect...