PURPOSE To evaluate a series of patients with corneal ectasia after LASIK that underwent the Athens Protocol: combined topography-guided photorefractive keratectomy (PRK) to reduce or eliminate induced myopia and astigmatism followed by sequential, same-day ultraviolet A (UVA) corneal collagen cross-linking (CXL). METHODS Thirty-two consecutive corneal ectasia cases underwent transepithelial ...

BACKGROUND/AIMS Epithelial debridement for photorefractive keratectomy (PRK) is associated with pain, slower visual recovery, and may be aetiological in haze production. The aim of this study was to assess the clinical results of a new technique involving raising and replacing of an epithelial flap in photorefractive keratectomy. METHODS A prospective, non-randomised, comparative, paired eye ...

PURPOSE To compare the outcome of photorefractive keratectomy (PRK) and complications in patients treated with either loteprednol etabonate 0.5% gel or prednisolone acetate 1% suspension and fluorometholone (fml) 0.1% suspension. SETTING John A Moran Eye Center, University of Utah, Salt Lake City, UT, USA. DESIGN Prospective, randomized, partially masked trial. METHODS PRK was performed o...

PURPOSE Corneal myofibroblasts differentiated from activated corneal stromal cells are the major cellular sources of extracellular matrix synthesis for the repair of corneal injury. In this study, the effects of histone deacetylase (HDAC) inhibitors on the activation, proliferation, migration and senescence of corneal stromal cells were evaluated. METHODS Primary human and mouse corneal strom...

although the majority of the cornea was nonedematous, there was marked corneal edema in the area of the GV markings with bulla noted (Figure 1). Over several weeks, the edema gradually resolved with interface haze in the area of prior edema. The visual acuity resolved to 20/40 without correction. Case 2. A 67-year-old woman with a history of Fuchs endothelial dystrophy presented with gradual on...

PURPOSE To report the efficacy, safety, predictability and complications of photorefractive keratectomy (PRK) with intraoperative application of mitomycin-C (MMC). METHODS This historical cohort study was performed on 1,250 eyes of 625 patients who underwent PRK using the Technolas 217 excimer laser machine by a single surgeon with intraoperative use of MMC 0.02% up to 2 minutes, depending on...

PURPOSE To examine the effectiveness, safety, and stability of laser subepithelial keratomileusis (LASEK), a modified photorefractive keratectomy for low to moderate myopia. METHODS This study evaluated the results of LASEK in 48 myopic patients (84 eyes) with a consecutive 6-month follow-up period. Preoperative myopia ranged from 3.25 to 7.00 diopters (D). Uncorrected and corrected visual ac...

PURPOSE Corneal thinning disorders weaken the mechanical strength of affected corneas, suggesting that photorefractive procedures may be contraindicated in keratoconus. Few cases have been reported to confirm this hypothesis. METHODS A 45-year-old man had two laser in situ keratomileusis (LASIK) procedures and one photorefractive keratectomy (PRK) performed on his left eye, and three LASIK pr...

PURPOSE To evaluate the long-term results of accelerated corneal cross-linking (CXL) in patients with progressive keratoconus. METHODS Sixteen patients underwent accelerated CXL at 6 mW/cm(2) for 15 minutes in one eye. The follow-up visits were scheduled on 7 days, 14 days, and 3, 12, and 24 months after the treatment. RESULTS There were no significant differences (P > 0.05) between preoper...