This study presents the development of the corneal epithelium of the mouse in chronological sequence covering the early prenatal, late prenatal, and postnatal periods, until the time of the disappearance of lid adhesion. The work is based on electron microscopic study of the corneal epithelium at daily intervals from the eleventh day of gestation to the seventh postnatal day, as well as the ten...

BACKGROUND A pilot study was carried out in Pakistan to assess the feasibility of the use of lathed freeze-dried corneal tissue in the treatment of corneal scarring. METHOD Six eyes underwent lamellar keratoplasty and were followed up for 18 months. RESULTS Visual improvement was obtained in every eye. In one eye, the procedure was complicated by delayed epithelialization of the graft, but ...

PURPOSE Bevacizumab is a potent recombinant humanized monoclonal antibody directed against vascular endothelial growth factor (VEGF). The purpose of this study was to evaluate the therapeutic effect of subconjunctival injection of bevacizumab on corneal neovascularization (NV) in different rabbit models. METHODS Several rabbit models of corneal NV were used, including (1) a corneal micropocke...

Background: The effect of corticosteroid therapy on corneal wound healing is controversial. The objective of this study was to evaluate the effects of combination therapy with dexametha-sone and acetylcysteine at different times and durations on experimentally-induced corneal wounds and haze in rabbits. Methods: Eighteen adult New Zealand white rabbits were divided into three groups of ...

PURPOSE To characterize changes in corneal collagen arrangement during mouse postnatal development. METHODS Small-angle X-ray scatter patterns were gathered from the centers of 32 excised mice corneas aged between postnatal days 10 (before eye opening) and 28 (onset of sexual maturity). These were analyzed to produce measurements of the average separation distance between corneal collagen fib...

PURPOSE To investigate and map the polarizing properties of keratoconus corneas in vitro and to compare the results with those obtained in normal corneas. METHODS Corneal buttons of five keratoconus corneas were investigated by polarization-sensitive optical coherence tomography (PS-OCT). The instrument measures backscattered intensity (conventional OCT), retardation, and (cumulative) slow ax...

A new method was developed for the analysis of fluorescein exchange between the aqueous humor and cornea which enables calculation of the permeability coefficient of the corneal endothelium and the steady-state aqueous-cornea distribution ratio from one experiment. After intravenous fluorescein injection, aqueous and corneal fluorescence was measured at intervals, using an objective fluorophoto...

three activated carbons are synthesized in a rotary reactor at different activation times. the adsorption isotherms of the samples are measured the pore size distribution of the samples is determined using combined saito and foley method, bjh method. an average potential function has been determined inside the cylindrical pores. the effect of activation time on the pore size distribution sample...