STUDY OBJECTIVE Disturbance in blood glucose homeostasis during cardiac surgery may cause visceral and metabolic alterations. Hypothermic CPB induces glucose and hormonal changes. As normothermic CPB is used at some institutions, a comparison of blood glucose and plasma hormones between hypothermic and normothermic CPB was performed. DESIGN Prospective nonrandomized study. SETTING Universit...

Surgical correction of congenital cardiac malformations or aortocoronary bypass surgery in many cases implies the use of cardiopulmonary-bypass (CPB). However, a possible negative impact of CPB on internal organs such as brain, kidney, lung and liver cannot be neglected. In general, CPB initiates a systemic inflammatory response (SIRS) which is presumably caused by contact of blood components w...

The hybrid failure is a coupled mechanism under the action of tensile and shear stresses. critical in cemented paste backfill (CPB) since there are no visible signs prior to failure. Few studies have been conducted on stress response CPB. This most likely due lack suitable laboratory equipment test procedures. paper presents new punching apparatus evaluate We harness two-dimensional finite elem...

In the course of cardiac surgery with cardiopulmonary bypass (CPB) many factors come into play. A lot care is needed, in addition to itself, especially regard blood oxygenation, pressure and formation microemboli, which will directly influence pathogenesis neurological abnormalities found postoperative period. Elevations values ​​of intracranial (ICP) adults can be small severe, may pose a thre...

Clostridium perfringensβ-toxin (CPB) is the major virulence factor of C.perfringens type C causing a hemorrhagic enteritis in animals and humans. In experimentally infected pigs, endothelial binding of CPB was shown to be associated with early vascular lesions and hemorrhage but without obvious thrombosis of affected vessels, suggesting altered hemostasis in the early phase of the disease. The ...

Objective(s): To study the effect of cardiopulmonary bypass (CPB) on nuclear factor-kappa B (NF-кB) and cytokine expression and pulmonary function in dogs. Materials and Methods: Twelve male mongrel dogs were divided into a methylprednisolone group (group M) and a control group (group C). All animals underwent aortic and right atrial catheterization under general anesthesia. Changes in pulmonar...

This paper discusses a widely used discrete-time analog of dynamic continuous-time models. This analog can not be used for the estimation of models with fast adaption to shocks. This has been overlooked in the econometric literature. The engineering literature on the same subject is also discussed, which includes warnings against the estimation of fast models. The engineering literature is igno...

The rheological properties (yield stress, flow index and infinite dynamic viscosity) mechanical (unconfined compressive strength, UCS) of different cemented paste backfill (CPB) recipes must be determined during the laboratory optimization phase. However, influence mixing procedure on these has scarcely been studied so far. objective this paper is to assess what extent depend specific energy (S...

Acute normovolemic hemodilution (ANH) is a blood-conservation method in which whole blood (WB(ANH)) is sequestered into blood collection bags before the commencement of surgery. However, for cardiac surgery, extracorporeal circuit (ECC) priming techniques limit the amount of blood that may collected prior to the actual initiation of cardiopulmonary bypass (CPB). In this study, computational mod...

BACKGROUND Heat-shock protein 70 (HSP70) plays a major role in the pathophysiology of inflammation, and the induction of HSP70 before the onset of inflammation can reduce organ damage through a self-protective system. Glutamine is known to be an inducer of HSP70, and its preoperative administration seems useful in attenuating cardiopulmonary bypass (CPB)-induced inflammatory response. METHODS...