ing the duplication generates increased levels of EFNB1 transcript, compared to the normal chromosome. We also show that imbalance of ephrin-B1 between X chromosomes in a mouse model containing a hypomorphic Efnb1 conditional allele results in aberrant cell mixing of the cranial primordia during development and hypertelorism. Taken together these data suggest that cellular mosaicism for differe...

BACKGROUND Dental caries is a chronic disease among children and there is need for studies assessing the caries risk factors using saliva. This study aimed to evaluate the association of salivary soluble CD14 and dental caries in young children. MATERIAL AND METHODS A cross-sectional study was done among 300, 3-6 year old school children of Udupi district. A total of 40 children who were cari...

Management of the airway in neonatal patients with craniofacial abnormalities or facial dysmorphism presents a challenge to health care providers. These patients may require specialized equipment and techniques to secure the airway safely. Video laryngoscopy with standard pediatric sized blades is a newly available and emerging technology and may serve as another tool when a potentially difficu...

OBJECTIVE To describe the novel use of a delayed chondrofascial flap to increase auricular projection in microtia reconstruction. METHODS Retrospective survey analysis. Ten consecutive children with unilateral microtia without other craniofacial abnormalities were followed up for a period ranging from 6 months to 5 years after microtia reconstruction was performed with the newly described del...

We introduce the Ontology of Craniofacial Development and Malformation (OCDM), a project of the NIH-funded FaceBase consortium, whose goal is to gather data from multiple species, at levels ranging from genes to gross anatomy, in order to understand the causes of craniofacial abnormalities. The OCDM is being developed in order to facilitate integration of these diverse forms of data in a centra...

The objective of this study was to supply information about: (1) normal sex-related dimensions of ears (linear distances and ratios, area); (2) left-right symmetry; and (3) growth changes between childhood and old age. The three-dimensional coordinates of several soft-tissue landmarks on the ears and face were obtained by a non-invasive, computerized electromagnetic digitizer in 497 male and 34...

OBJECTIVE Silybum marianum has been used for centuries in herbal medicine for treatment of liver diseases. Currently, there is no data available on the possible effects of silymarin on fetal development. This study aimed to investigate the teratogenic effect of silymarin on BALB/c mice fetuses. MATERIALS AND METHODS A total of 40 pregnant mice were divided into 4 groups of 10 mice each. Three...

morning glory syndrome (mgs) is a rare congenital optic disc anomaly characterized by a funnel-shaped, excavated optic disc surrounded by chorioretinal pigmentary disturbance. the main ophthalomoscopic feature of the mgs is enlarged optic disc with a funnel shaped scleral defect; elevated peripapillary chorioretinal pigmentation; and pale fluffy tissue of glial hyperplasia overlying the optic d...

PURPOSE To develop an experimental surgical model in rats for the study of craniofacial abnormalities. METHODS Full thickness calvarial defects with 10x10-mm and 5x8-mm dimensions were created in 40 male NIS Wistar rats, body weight ranging from 320 to 420 g. The animals were equally divided into two groups. The periosteum was removed and dura mater was left intact. Animals were killed at 8 a...

background and aim: it is well - known that sex hormones regulate bone metabolism. sex steroids increase osteoblasts activities and affect growth, remodeling and bone homeostasis. the aim of this study was to examine the effects of sex hormones deficiency on craniofacial growth in rats. methods & materials: fifty, thirty–day–old wistar rats comprised the sample in this experimental study. 25 ma...