نتایج جستجو برای: craniospinal radiotherapy
تعداد نتایج: 62611 فیلتر نتایج به سال:
abstract background: adjacent treatment fields are commonly used in external beam radiation therapy, such as mantle and inverted-y fields for the treatment of hodgkin’s disease and craniospinal fields used in the treatment of medulloblastoma and head and neck tumors when the lateral neck fields are placed adjacent to the anterior supraclavicular field. in each of these situations, there is a po...
The impact of treatment with either cranial or craniospinal irradiation with or without cytotoxic chemotherapy for a brain tumour distant from the hypothalamic-pituitary axis was assessed in 29 children who had reached final height. All had received growth hormone treatment for radiation induced growth hormone deficiency. Final height, segmental growth during puberty, and duration of puberty we...
We present a case of craniospinal hypotension in a 45-year-old woman with an associated epidural pseudomeningocele extending the entire length of the spine. The epidural pseudomeningocele was caused by a CSF leak at the T8 level. In addition to typical low-pressure symptoms, the epidural pseudomeningocele caused atypical symptoms characterized by positional thoracic radiculopathy. Craniospinal ...
Medulloblastoma is the most common form of childhood brain tumor, and management has evolved over the past two decades. Chemotherapy is now an integral part of the treatment of the majority, if not all, patients with this disease. Medulloblastoma is a chemosensitive tumor, and recurrent disease will often respond to a variety of different chemotherapeutic agents. The use of higher-dose chemothe...
Abstract Reducing radiation-induced side effects is one of the most important challenges in paediatric cancer treatment. Recently, there has been growing interest using spatial normalisation to enable voxel-based analysis toxicities a variety patient groups. The need consider three-dimensional distribution doses, rather than dose-volume histograms, desirable but not yet explored populations. In...
Abstract Medulloblastoma (MB) is the most common type of malignant pediatric brain cancer. Current standard care (SOC) involves maximal safe resection and neuraxis radiotherapy chemotherapy in individuals older than 3 years. To date, these cytotoxic SOC combined with craniospinal irradiation led to devastating neurocognitive developmental deficits impacting quality life for patients. The biolog...
PURPOSE To estimate the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of escalating doses of temozolomide combined with O(6)-benzylguanine in patients < or =21 years with recurrent brain tumors. EXPERIMENTAL DESIGN Treatment strata consisted of patients who had previously received no or local radiotherapy (Str1) and patients who had undergone craniospinal radiotherapy or myelo...
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