We used the inositol 1,4,5-trisphosphate (IP3 ) biosensor, the pleckstrin homology (PH) domain of PLC 1 (phospholipase C) tagged with enhanced green fluorescent protein (eGFP-PHPLC ), to examine muscarinic acetylcholine (mACh) receptor regulation of phospholipase C/IP3 signaling in intact single hippocampal neurons in “real time.” Initial experiments produced a pharmacological profile consisten...

Determination of the path taken by a quantum particle leads to a suppression of interference and to a classical behavior. We employ here a quantum "which path" detector to perform accurate path determination in a two-path Mach-Zehnder electron interferometer, leading to full suppression of the interference. Following the dephasing process we recover the interference by measuring the cross corre...

In this research, a gas turbine blade cascade was investigated. Flow analysis around the blade was conducted using RSM and RNG.K-ε turbulence modeling and it is simulated by Fluent software. The results were considered for the cases as Mach number loss at the trailing edge of blade caused by vortexes that were generated at the end of blade. Effect of cooling flow through the trailing edge on th...

A preconditioned five-equation two-phase model coupled with an interface sharpening technique is introduced for simulation of a wide range of multiphase flows with both high and low Mach regimes. Harten-Lax-van Leer-Contact (HLLC) Riemann solver is implemented for solving the discretized equations while tangent of hyperbola for interface capturing (THINC) interface sharpening method is applied ...

Generation of repeatable pseudo-random sequences with chaotic analog electronics is not feasible using standard circuit topologies. Component variation caused by imperfect fabrication causes the same divergence of output sequences as does varying initial conditions. By quantizing the output of a simple chaotic difference equation and using delayed feedback, we are able to construct a circuit wh...

We give a comparison of various di erential cross{section models for a classical polyatomic gas for a homogeneous relaxation problem and the shock wave pro les at Mach numbers 1.71 and 12.9. Besides the standard Borgnakke{Larsen model and its generalization to an energy dependent coe cient to control the amount of rotationally elastic and completely inelastic collision, we discuss some new mode...

A probe consisting of two poloidally separated triple probes and a Mach probe ~TMT probe! has been designed and installed on the H-1 heliac to study fluctuations. Mach probes are shown to be sensitive to the fluctuations in the electron density, electron and ion temperatures, and ion drift velocity. If the ion Larmor radius is much larger than the characteristic probe dimension, then the Mach p...

Direct numerical simulations (DNS) are carried out to study the laminar stability properties of an effusioncooled adiabatic flat-plate boundary layer at Mach 6. Through four aligned rows of holes, cold gas is blown into the boundary layer at the wall and background disturbances are excited at the wall upstream of the holes. Two cases are compared, with small and large spanwise spacing of the ho...

A spatial domain optimal trade-off Maximum Average Correlation Height (OT-MACH) filter has been previously developed and shown to have advantages over frequency domain implementations in that it can be made locally adaptive to spatial variations in the input image background clutter and normalised for local intensity changes. In this paper we compare the performance of the spatial domain (SPOT-...