The thyroid-stimulating hormone (TSH) receptor (TSHR) is a member of the glycoprotein hormone receptors (GPHRs), a sub-group of class A G protein-coupled receptors (GPCRs). TSHR and its ligand thyrotropin are of essential importance for growth and function of the thyroid gland. The TSHR activates different G-protein subtypes and signaling pathways, of which Gs and Gq induced signaling are of hi...

ion, and must sometimes appear to be an unaffordable luxury to a fair portion of the world’s population, irrespective of ideology, tradition, or social status. And yet, while the temptation is to exhort scientific enquiry and design – push on, push as hard, as fast and as far as you can we are obliged also to pause, Ethics, Bio-Ethics and Environment in Healing Designs ....... African Journal o...

La historiografía sobre fortificaciones medievales en el ámbito medieval cristiano es tan amplia como dispersa. Abundan los estudios de carácter local abordados con metodologías y desde disciplinas diversas, empezando por clásicos trabajos Historia del Arte e la Arquitectura, y, supuesto, contenido estrictamente histórico, planteados estudio las fuentes escritas más recientemente, Arqueología. ...

In his paper, "Qu(e)erying Comic Book Culture and Representations of Sexuality in Wonder Woman," Brian Mitchell Peters proposes that youth culture is responsible for an arbitrary yet highly structured appropriation of what we can call high-contemporary culture. Hence, notions of pop-culture take from the past and use the present to create a highly fluid now, capable of transcending its present ...

In 2019 there existed a legal entity known as The Church of Jesus Christ Latter-day Saints.1 This fact will likely strike most readers unexceptional. More interesting, however, prior to had been no such the Saints for over 150 years, last that name having disincorporated in 1862. Even more strangely, although were millions people around globe who identified themselves Saints, only member was Ru...

This article rebuts conventional claims that AIDS in Africa is a microbial problem to be controlled through sexual abstinence, behavior modification, condoms, and drugs. The orthodox view mistakenly attributes to sexual activities the common symptoms that define an AIDS case in Africa diarrhea, high fever, weight loss and dry cough. What has really made Africans increasingly sick over the past ...

A significant topic in American political discourse is that of law and order. Politicians, civic leaders, and policy makers often propose a hard-line towards crime so that “law and order” is maintained. In this essay, I contend that the discourse of “law and order” has taken on mythic properties in American political discourse, and that the media, in large part, has contributed to the creation ...

The emergence of new non-state actors in the post Cold War reality have dramatically changed security environment around the globe. Modern terrorism practiced by Al Qaeda and its associated movement (AQAM) has posed serious threat to critical information infrastructure given the trend of connecting control systems that run these infrastructures to the internet. Although AQAM have not been succe...