نتایج جستجو برای: cryptococcosis
تعداد نتایج: 1868 فیلتر نتایج به سال:
Cryptococcus gattii is an emergent human pathogen. Fluconazole is commonly used for treatment of cryptococcosis, but the emergence of less susceptible strains to this azole is a global problem and also the data regarding fluconazole-resistant cryptococcosis are scarce. We evaluate the influence of fluconazole on murine cryptococcosis and whether this azole alters the polysaccharide (PS) from cr...
BACKGROUND The clinical manifestation of pulmonary cryptococcosis varies notably between immunocompromised and immunocompetent patients. To better understand pulmonary cryptococcosis, we compared the clinical features of pulmonary cryptococcosis patients with or without decreased peripheral blood CD4+ T cell counts. METHODS We retrospectively reviewed the medical records of 80 patients with c...
Correspondence: Dr Amit Agrawal Associate Professor of Neurosurgery, Department of Neurosurgery, K.S. Hegde Medical Academy, Nityananda Nagar, Mangalore-575108, Karnataka,India. E-mail: [email protected] INTRODUCTION Cryptococcosis has dramatically increased in frequency as a result of the pandemic of human immunodeficiency virus (HIV) infection and an enlarging population of other immuno...
A 68-year-old man had multiple left pulmonary nodules with serum positivity for proteinase 3 anti-neutrophil cytoplasmic autoantibody (PR3-ANCA) and negativity for cryptococcal antigen (Picture 1). We initially regarded him as having granulomatosis with polyangiitis (GPA). He subsequently underwent a video-assisted surgical lung biopsy for the diagnosis (Picture 1, arrowheads). Hematoxylin and ...
Cryptococcosis is an invasive and opportunistic systemic mycosis. It transmitted by fungi of the genus Cryptococcus, acquired inhalation causes infection or lodging in lungs. can present asymptomatically with various symptoms cases immune deficiency, such as those caused diabetes, it reactivate tend to develop into meningoencephalitis disseminated disease. The aim this study was evaluate epidem...
Cryptococcosis is not uncommon, especially among immunocompromised patients. However, placental cryptococcosis rare, with few reported cases in the literature. A 21 yr. old primigravida, a known case of HIV was admitted to hospital at 36 weeks gestation for antepartum hemorrhage. Her vital signs were within normal limits. laboratory investigations revealed hemoglobin-6 gm%. The peripheral smear...
Cryptococcus neoformans is an encapsulated fungus that causes cryptococcosis. Central nervous system infection is the most common clinical presentation followed by pulmonary, skin and eye manifestations. Cryptococcosis is primarily treated with amphotericin B (AMB), fluconazole (FLC) and itraconazole (ITC). In the present work, we evaluated the in vitro effect of terbinafine (TRB), an antifunga...
BACKGROUND Cryptococcosis is a life-threatening opportunistic fungal infection in both HIV-positive and -negative patients. Information on clinical presentation and therapeutic guidelines, derived mostly from clinical trials performed before introduction of highly active antiretroviral therapy in patients with cryptococcal meningoencephalitis, is missing data on extrameningeal involvement and i...
Cryptococcosis occurs most frequently in immunocompromised individuals. This has led to the prevailing view that this disease is the result of weak immune responses that cannot control the fungus. However, increasingly, clinical and experimental studies have revealed that the host immune response can contribute to cryptococcal pathogenesis, including the recent study of L. M. Neal et al. (mBio ...
BACKGROUND Risk factors including how changes in immunosuppression influence the occurrence of immune reconstitution syndrome (IRS) in solid organ transplant (SOT) recipients with cryptococcosis have not been fully defined. METHODS SOT recipients with cryptococcosis were identified and followed for 12 months. IRS was defined based on previously proposed criteria. RESULTS Of 89 SOT recipient...
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