BACKGROUND Inflammation plays a critical role in lung disease development and progression in cystic fibrosis. Azithromycin is used for the treatment of cystic fibrosis lung disease, although its mechanisms of action are poorly understood. We tested the hypothesis that azithromycin modulates lung inflammation in cystic fibrosis mice. METHODS We monitored cellular and molecular inflammatory mar...

Cystic breast mass is one of the common conditions seen presented in any breast clinic. Evaluating such cystic breast lesions is very important. Malignant cystic tumors like mucinous carcinomas and papillary carcinomas have to be differentiated from common benign cystic lesions of the breast like fibrocystic lesions and papillomas. Malignant breast cancers that present as cystic lesions are see...

Purpose of review Over the past four decades, outcomes for patients with cystic fibrosis have improved dramatically. Major contributors to this improvement are a better understanding of disease pathogenesis and the systematic conduct of clinical trials evaluating new therapies designed to address these defects. This review describes recent developments in cystic fibrosis pulmonary therapies int...

Pseudoaneurysm of a cystic artery is a rare entity that commonly occurs secondary to biliary procedures. Most of the cases in literature are consisted of ruptured aneurysms and to our knowledge, except our case, there were only 3 cases with unruptured aneurysms, which incidentally were detected by radiological methods. When cystic artery pseudoaneurysm is present with acute cholecystitis, most ...

Context Mucinous cystic neoplasms are cystic lesions of the pancreas with a relevant risk to progress to invasive cancer. Mucinous cystic neoplasms are characterized by the presence of an ovarian-like stroma and its almost exclusive occurrence in women. Case report Here we report the case of a 41-year old patient with a known cystic lesion that became symptomatic briefly after pregnancy. A panc...

Cystic fibrosis in patients over 40 is rare. We report a 52-year-old woman in whom cystic fibrosis was confirmed by sweat analysis. This patient represents the oldest cystic fibrosis patient (with confirmatory sweat chlorides) ever described. We conclude that any patient with the appropriate clinical presentation, regardless of age, should be investigated for cystic fibrosis.

Purpose : Only a few studies on diffusion weighted (DW) imaging of ovarian lesions have been reported (1-3). In previous studies, the role of DW imaging in distinguishing between benign and malignant cystic tumors may be limited. Katayama et al (3) reported that apparent diffusion coefficient (ADC) values may not provide additional information, especially to discriminate benign from malignant l...

congenital cystic lesions of the pancreas are rare findings. furthermore, dermoid cyst of the pancreas is exceptionally uncommon. a review of the world literature showed that only 18 documented cases of dermoid cyst of the pancreas were reported so far. the pre-operative evaluation of this lesion is rather questionable, with definitive diagnosis taking place intra-operatively. herein, we presen...

adenoid cystic carcinoma of the lung is a relatively rare, slow growing lung neoplasm. metastases outside the lung are uncommon. herein, we have reported the case of a patient who presented with a large mass in the right lower lobe of her lung. bronchial biopsy revealed features suggestive of adenoid cystic carcinoma of the lung with a predominant cribriform architecture. ct abdomen showed feat...

We report 12 cases of renal cystic lesions that could not be diagnosed preoperatively. Sonography, computed tomography (CT), magnetic resonance (MR) imaging, and angiography were performed in all cases. Angiography was not helpful in evaluating cystic lesions, because all cystic lesions were hypovascular or avascular within the cystic mass. CT was useful in depicting the fine structural abnorma...